单、双胎妊娠并发子痫前期临床分析

目的探讨单、双胎妊娠并发子痫前期的临床特点及妊娠结局。 方法选取2009年1月至2013年4月在广州医科大学附属第三医院产科住院分娩的43例双胎并发子痫前期的孕妇为研究组，362例单胎并发子痫前期产妇作为对照组，回顾性分析两组患者的临床特点及母婴结局的情况。 结果研究组住院时间(13.28±11.23)d，较对照组(9.48±4.97)d延长，t＝2.20，P<0.05。研究组剖宫产率、胎膜早破、产后出血、心力衰竭的发生率分别为97.67%、13.95%、11.63%、11.63%，明显高于对照组(79.83%、5.25%、5.25%和4.14%)，差异有统计学意义(P<0.05)。研究组发生新生儿感染和黄疸分别为25.58%和48.84%，高于对照组15.19%和32.60%，差异有统计学意义(P<0.05)。 结论双胎并发子痫前期与单胎并发子痫前期相比，会增加孕产妇的剖宫产、胎膜早破、产后出血、心力衰竭等发生率，同时延长产妇的住院时间。

Clinical analysis of single or twin pregnancy complicated with preeclampsia

ObjectiveTo explore the clinical features and pregnancy outcomes of single or twin pregnancy complicated with preeclampsia. MethodsFrom January 2009 to April 2013, 405 pregnancies complicated with preeclampsia, who were admitted to the Obstetrics department of the Third Affiliated Hospital of Guangzhou Medical University were enrolled in this retrospective study. This study included 43 twin pregnancies in research group and 362 singleton pregnancies in the control group. The clinical features and pregnancy outcomes of the two groups were retrospectively analyzed. ResultsThe length of hospital stay in research group and control group were (13.28±11.23) day and (9.48±4.97) day, respectively. There was significant difference in the two groups (t=2.20, P<0.05). In research group, the incidence of cesarean section, premature rupture of membranes, postpartum hemorrhage, heart failure were 97.67%, 13.95%, 11.63% and 11.63%, respectively, which were higher than that in control group (79.83%, 5.25%, 5.25% and 4.14%) with significant difference (P<0.05). In research group, the incidence of newborn infection and jaundice were 25.58% and 48.84%, which were higher than that in control group (15.19% and 32.60%) with significant difference (P<0.05). ConclusionCompared to singleton pregnancy complicated with preeclampsia, twin pregnancy complicated with preeclampsia increased the incidence of cesarean section, premature rupture of membranes, postpartum hemorrhage and heart failure, and extended maternal hospital stay.