Clinical Impact of Multiplex Syndromic Panels in the Diagnosis of Bloodstream,Gastrointestinal, Respiratory,and Central Nervous System Infections |
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Authors: | April N Abbott Ferric C Fang |
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Institution: | 1. Deaconess Health System and Indiana University School of Medicine, Evansville, Indiana;2. Departments of Laboratory Medicine and Microbiology, University of Washington School of Medicine, Seattle, Washington |
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Abstract: | Recent technological advances are revolutionizing clinical microbiology. In place of the traditional diagnostic approach in which a clinician suspecting an infectious disease is required to test for the most likely etiology, perform follow-up testing for rarer causes, and then perhaps be left with a diagnosis of exclusion, many laboratories are now offering multiplex syndromic panels to provide a comprehensive diagnostic approach to bloodstream, gastrointestinal, respiratory, and central nervous system infections. In addition to simplifying testing and laboratory workflow, multiplex panels can improve patient care, promote antimicrobial stewardship, and assist with infection control and prevention. This review discusses the growing body of evidence demonstrating the clinical impact and cost-effectiveness of multiplex panels. |
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Keywords: | Corresponding Author: Ferric C Fang Department of Microbiology University of Washington School of Medicine 1959 NE Pacific Street Box 357735 Seattle WA 98195-7735 Tel : 206-221-6770 Fax: 206-616-1575 |
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