| 微生物来源的抗真菌抗生素的研究进展 |
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| 引用本文： | 殷瑜,黄为一,陈代杰.微生物来源的抗真菌抗生素的研究进展[J].中国新药杂志,2004,13(2):113-117. |
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| 作者姓名： | 殷瑜 黄为一 陈代杰 |
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| 作者单位： | 1. 南京农业大学微生物学系,南京,210095
2. 上海来益生物药物研发中心,上海,201203 |
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| 摘 要： | 近年来,随着真菌感染性问题的日趋严重,研究开发安全、新型和有效的抗真菌药物显得尤为重要.抗真菌药物根据其作用靶位分为抑制真菌细胞膜、细胞壁、蛋白质和核酸合成及抑制电子传递等5种类型.现从这5个方面对微生物来源的抗真菌抗生素研究进展作一概述.
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| 关 键 词： | 抗真菌抗生素 细胞膜 细胞壁 蛋白质 电子传递 核酸合成 |
| 文章编号： | 1003-3734(2004)02-0113-05 |
Development in research of antifungal antibiotics derived from microorganisms |
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| YIN Yu,HUANG Wei-yi,CHEN Dai-jie.Development in research of antifungal antibiotics derived from microorganisms[J].Chinese Journal of New Drugs,2004,13(2):113-117. |
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| Authors: | YIN Yu HUANG Wei-yi CHEN Dai-jie |
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| Abstract: | With the problem of fungal infections getting increasingly serious,it's important to develop novel safe and effective antifungal drugs. According to defferent action targets including cell membrane, cell wall, protein, nucleic acid and electron transport, anti fungal antibiotics were divided into five types. The development in research of these five types of antibiotics derived from microorganisms was reviewed in this paper. |
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| Keywords: | antifungal antibiotics cell membrane cell wall protein electron transport nucleic acid synthesis |
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