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| 黄连解毒汤不同剂型抗菌药效实验研究 | |
| 引用本文： | 罗海燕,邝枣园,李岩,黄暨生,黄少伟,李明. 黄连解毒汤不同剂型抗菌药效实验研究[J]. 医疗保健器具, 2011, 18(5): 647-648. DOI: 10.3936/j.issn.1674-4659.2011.05.0647 |
| 作者姓名： | 罗海燕 邝枣园 李岩 黄暨生 黄少伟 李明 |
| 作者单位： | 1. 广州中医药大学基础医学院,广东,广州,510006 2. 广东药学院基础学院,广东,广州,510006 |
| 基金项目： | 广东省自然科学基金，广东省医学科研基金 |
| 摘 要： | 目的从体外抗菌效果的角度比较黄连解毒汤颗粒剂和黄连解毒汤煎剂两种剂型的药效。方法用试管内药液两倍稀释法分别测定黄连解毒汤颗粒剂和黄连解毒汤煎剂对不同细菌的最小抑菌浓度（MIC）。结果两种剂型对各实验菌的MIC分别为：黄连解毒汤颗粒剂介于0.0020～0.5000g·ml-1;黄连解毒汤煎剂对大肠埃希氏菌不敏感（〉0.50g·ml-1）,对其余实验菌介于0.0078～0.1250g·ml-1。结论黄连解毒汤颗粒剂的抑菌作用优于黄连解毒汤煎剂,可以作为黄连解毒汤煎剂的替代品。 |
| 关 键 词： | 黄连解毒汤 颗粒剂 煎剂 最小抑菌浓度 |
Study on the Antibacterial Effect of Huang-Lian-Jie-Du-Tang in Different Dosage-forms |
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| LUO Haiyan,KUANG Zaoyuan,LI Yon,HUANG Jisheng,HUANG Shoowei,LI Ming. Study on the Antibacterial Effect of Huang-Lian-Jie-Du-Tang in Different Dosage-forms[J]. Medicine Healthcare Apparatus, 2011, 18(5): 647-648. DOI: 10.3936/j.issn.1674-4659.2011.05.0647 | |
| Authors: | LUO Haiyan KUANG Zaoyuan LI Yon HUANG Jisheng HUANG Shoowei LI Ming |
| Affiliation: | LUO Haiyan 1,KUANG Zaoyuan 1,LI Yan 1,HUANG Jisheng 1,HUANG Shaowei 1,LI Ming 2(1School of Basic Medical Science,Guangzhou University of TCM,Guangzhou 510006,China,2Basic College,Guangdong Pharmaceutical University,China) |
| Abstract: | Objective To compare the different antibacterial effects of Huang-Lian-Jie-Du-Tang in different dosage-forms.Methods The minimal inhibitory concentration（MIC） of Huang-Lian-Jie-Du-Tang in different dosage-forms to different kinds of bacterium was detected by tube dilution method.Results MIC of Huang-Lian-Jie-Du-Tang granule was from 0.0020 to 0.5000 g·ml-1,MIC of Huang-Lian-Jie-Du-Tang decoction was from 0.0078 to 0.1250 g·ml-1.Conclusion Judging from the results,the antibacterial effect of granule is better than decoction.Therefore,Huang-Lian-Jie-Du-Tang granule should be a alternative to Huang-Lian-Jie-Du-Tang decoction. |
| Keywords: | Huang-Lian-Jie-Du-Tang Granule Decoction Minimal inhibitory concentration |
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