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Endogenous Endophthalmitis in the American and Korean Population: An 8-year Retrospective Study |
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| Authors: | Heeyoon Cho Yong Un Shin Nicole H. Siegel Hyeong Gon Yu Lucia Sobrin Achal Patel |
| Affiliation: | 1. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA;2. Department of Ophthalmology, Hanyang University Medical College, Seoul, Republic of Korea;3. Department of Ophthalmology, Hanyang University Medical College, Seoul, Republic of Korea;4. Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA;5. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea |
| Abstract: | Purpose: To study the clinical features of endogenous endophthalmitis (EE) in sample patient populations from the USA and South Korea over an 8-year period. Methods: We reviewed data from 128 eyes of 60 American and 48 Korean patients diagnosed with EE and compared their clinical characteristics. Results: Fungemia and liver abscess were the most common extraocular infection sources among American (26.7%) and Korean patients (33.3%), respectively. Klebsiella pneumoniae and Candida species were the most common pathogens of EE in the Korean and the American patients, respectively. Endophthalmitis caused by fungi had a better visual prognosis than that caused by bacteria (p = 0.001). Vitrectomy was beneficial for eyes with EE due to virulent bacteria presenting with worse than counting finger vision. Conclusions: The predisposing conditions and responsible organisms for EE vary in different regions of the world. The visual prognosis was strongly influenced by the underlying pathogen. |
| Keywords: | Endogenous endophthalmitis infectious vitrectomy |