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丙泊酚和咪唑安定用于ICU病人镇静的临床观察
引用本文:杨建明,黄云巧. 丙泊酚和咪唑安定用于ICU病人镇静的临床观察[J]. 中国保健营养, 2012, 0(10): 1507-1508
作者姓名:杨建明  黄云巧
作者单位:昆明市第二人民医院麻醉科;昆明医学院第一附属医院急诊科
摘    要:目的评价丙泊酚和咪唑安定在ICU病人镇静的效果和安全性。方法给予患者应用丙泊酚组(P组)负荷量1.00-1.50㎎/㎏,维持量为0.50-3.00㎎.㎏-1.h-1,咪唑安定组(M组)负荷量0.05-0.30㎎/㎏,维持量为0.04-0.20㎎.㎏-1.h-1,控制患者于Ramsay评分Ⅲ-Ⅳ级。结果两组病人镇静效果佳,但在药物起效时间等方面两组比较呈显著差异(P<0.05)。结论在对患者进行麻醉时咪唑安定适用于患者的心血管情况不好,且要进行镇静的时间比较长。应用丙泊酚可适用于患者心血管情况比较好、对其镇静的时间比较短的。

关 键 词:镇静治疗  ICU  丙泊酚  咪唑安定

Observation of Propofol and Midazolam Applied in ICU
YANG Jiang-ming,HUANG Yun-qiao. Observation of Propofol and Midazolam Applied in ICU[J]. China Healthcare & Nutrition, 2012, 0(10): 1507-1508
Authors:YANG Jiang-ming  HUANG Yun-qiao
Affiliation:1.Anesthesiology Department of No.2 People’s Hospital of Kunming City,650204;2.Emergency Department of The First Affiliated Hospital Of Kunming Medical College,650031
Abstract:Objective To observe the efficacy and safety of propofol and midazolam for patient’s calmness in ICU.Methods In group P,loading capacity is 1.00-1.50㎎.㎏-1and maintain capacity is 0.50-3.00㎎.㎏-1.h-1.In group M with loading capacity is 0.05-0.30㎎.㎏-1,maintain capacity is 0.04-0.20㎎.㎏-1.They were controlled in Ransay Ⅲ-Ⅳclass.Results All patients were calmed satisfactorly,but two groups different fron maintain effect of medicament etc(P<0.05).Colclusion Propofol had better use to calm patient no long time and they are strong with circulatory system.However,midazolam is on the contrary.
Keywords:Calmative cure  ICU  Propofol  Midazolam
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