异丙酚复合氯胺酮持续输注在小儿静脉全麻的应用与评价

目的评估异丙酚复合氯胺酮静脉麻醉用于婴幼儿手术的麻醉效果。方法选60名患儿术前30min肌注阿托品0．02mg／kg，术中持续静脉输注异丙酚2-4mg／kg、氯胺酮1-2mg／kg维持麻醉状态，并观察术中平均动脉压（MAP）、心率（HR）、脉搏血氧饱和度（SpO2）及呼吸频率（RR）的变化。结果术中各时间与术前比较MAP、HR、SpO2、RR无显著差异性（P〉0．05），术中各时间间比较差异亦无显著性（P〉0．05）。结论异丙酚复合氯胺酮静脉全身麻醉效果满意，是一种安全、有效的婴幼儿手术麻醉方式。

The application and evaluation of propofol combined with ketamine bycontinous intravenous Infusion in infant surgery

Objective To assess propofol combined with ketamine anesthesia for surgery in infants of narcotic effect. Methods Anesthesia was maintained by continuous intravenous infusion of propofol 2～4 mg/kg and ketaminel ～2 mg/kg in 60 children, and atropine 0.02 mg/kg was given by the intramuscular injection before 30 minutes preoprative. The changes of the mean arterial pressure(MAP) ,heart rate(HR) ,pulse oxygen saturation(SpO2)and respiratory rate(RR) was observed. Results There was no significant difference between preoperative and different time during operation(P>0.05), and There was no significant difference between dif-ferent time during operation (P>0.05). Conclusion Continuous intravenous infusion of propofol combined with ketamine is safe and effective in infant surgery. The anesthetic effect was satisfied.