|
|||||
|
|
| 汉族和哈萨克族靶控输注丙泊酚浓度差异的观察 | |
| 引用本文： | 孙虎,王炜,徐志新. 汉族和哈萨克族靶控输注丙泊酚浓度差异的观察[J]. 临床麻醉学杂志, 2011, 27(3) |
| 作者姓名： | 孙虎 王炜 徐志新 |
| 作者单位： | 1. 新疆医科大学第一附属医院麻醉科,乌鲁木齐市,830011 2. 新疆油田公司明园职工医院药剂科 3. 海南省农垦总医院麻醉科 |
| 摘 要： | 目的 探讨新疆汉族、哈萨克族间民族差异对患者全麻诱导时不同镇静深度下靶控输注(TCI)丙泊酚效应室浓度(Ce)的影响.方法 拟行全麻的骨科患者42例,按民族分为两组:汉族组(H组)和哈萨克族组(K组),每组21例.麻醉诱导:两组患者均静注芬太尼后,TCI丙泊酚至脑电双频谱指数(BIS)降到40～50后静注维库溴铵,气管插管,机械通气.观察麻醉诱导前(T<,0>)、静注芬太尼4 rnin后(T<,1>)、意识消失时(T<,2>)、BIS降到40～50时(T<,3>)、静注维库溴铵4 min后(T<,4>)、气管插管即刻(T<,5>)、插管后1 min(T<,6>)、3 min(T<,7>)、5 min(T<,8>)时SBP、HR、BIS值和T<,2>、T<,3>时的丙泊酚Ce值及用药剂量.同时记录意识消失时间、达插管深度时间.结果 T<,2>、T<,3>时K组丙泊酚Ce高于H组(P<0.05);K组意识消失时间、达插管深度时间长于H组,丙泊酚用药量大于H组(P<0.01).结论 哈萨克族患者复合等量芬太尼麻醉诱导时不同镇静深度下所需TCI丙泊酚浓度较汉族患者大,临床麻醉中应区别用药. |
| 关 键 词： | 民族 丙泊酚 靶控输注 药效学 |
Observation of the difference of target effect-site concentration about propofol between Han and Kazak nationality |
|
| SUN Hu,WANG Wei,XU Zhi-xin. Observation of the difference of target effect-site concentration about propofol between Han and Kazak nationality[J]. The Journal of Clinical Anesthesiology, 2011, 27(3) | |
| Authors: | SUN Hu WANG Wei XU Zhi-xin |
| Affiliation: | SUN Hu,WANG Wei,XU Zhi-xin.Department of Anesthesiology,First Affiliated Hospital,Xinjiang Medical University,Urumqi 830011,China |
| Abstract: | Objective To investigate the effects of different ethnic on the target effect-site concentration of TCI propofol(Ce)at different sedation levels between Han and Kazak nationality during anesthesia induction.Methods 42 patients scheduled for orthepedics surgery with general anesthesia were randomly divided into 2 groups:group H(Han nationality,21 patients),group K(Kazak nationality,21 patients).Anesthesia was induced with injection of fentanyl and TCI of propofol until the BIS declined to 40-50,tracheal intu... |
| Keywords: | Ethnic Propofol Target-controlled infusion Pharmacodynamics |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |