肝内胆管囊腺癌临床病理特点及治疗(附12例报告)

目的：探讨肝内胆管囊腺癌临床病理特点及治疗方法。方法：回顾分析了12例肝内胆管囊腺癌的临床病理表现、诊治经验并结合文献资料加以讨论。结果：5例中可见局部癌细胞向囊璧外肝组织内浸润生长，另7例癌组织局限于囊壁内。12肝内胆管囊腺癌中7例行根治性手术切除，其中5例存活了5年，1例存活2年，另1例存活11个月；3例行肿块大部分切除，分别存活16，13，10个月；1例未能手术治疗，存活5个月；1例发现于尸检。5例存活超过5年者，其手术切除标本病理检查显示肿瘤生长均局限于囊壁内。结论：肝内胆管囊腺癌局限于囊肿内者，通过行肝切除完整肿块可获得较满意的临床疗效。

Clinicopathoiogic features and treatment of biliary cystadenocarcinoma of the liver

Objective To evaluate clinicopathologic features and treatment of biliary cystadenocarcinoma of the liver. Method Clinical situation, pathological features and therapeutic results of 12 cases of biliary cystadenocarcinoma of the liver were analysed retrospectively. Results 7 cases showed carcinoma cell proliferation confined to the cyst wall without any invasion into the liver parenchyma; in 5 cases ,the carcinoma cell extended to involve the surrounding liver tissue. Radical excision were performed in 7 cases, 5 cases of them were alive over 5 years, 1 case was alive for 2 years, and another for 11 months. In 3 cases ,the lesion couldn't be removed completely, they were survival for 16, 13 and 10 months respectively. Conclusions In the biliary cystadenocarcinoma confined to the cyst wall ,long-term survival could be achieved after surgical removal of the tumor by complete excision. [