| Effects of ambient pressure on the severity of blast injury in rats |
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| 作者姓名： | 杨志焕 尹友国 李晓炎 翁格文 刘大维 赵敏 |
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| 作者单位： | Research Institute of Field Surgery Third Military Medical College，Chongqing 630042，Research Institute of Field Surgery，Third Military Medical College，Chongqing 630042，Research Institute of Field Surgery，Third Military Medical College，Chongqing 630042，Research Institute of Field Surgery，Third Military Medical College，Chongqing 630042，Research Institute of Field Surgery，Third Military Medical College，Chongqing 630042，Research Institute of Field Surgery，Third Military Medical College，Chongqing 630042 |
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| 摘 要： | The effects of different ambient pressures of 53.99,61.33 and 96.60 kPa on theseverity of blast injury were observed in rats.It was found that when the incident shock wavewas 190.40 kPa in its peak pressure and 10 ms in its duration, both the mortality and the severityof lung injury were progressively increased along with the decrease of the ambient pressure.Themortality rate of the rats in the 6th hour after exposure was 0%,25% and 36.8% and the hem-orrhagic area on the lungs was 63.75+69.01,313.50+357.25 and 653.21+652.25 squaremilimeters when the ambient pressure was 96.60,61.33 and 53.99 kPa respectively.In addi-tion, the lung/body index was 0.93+0.21%,1.31+0.65% and 1.50+0.77% respectively.Itis believed that the decrease of the ambient pressure might decrease the tolerance of the rat to theimpact of blast waves to result in higher mortality and more extensive hemorrhage on the lungs.
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Effects of ambient pressure on the severity of blast injury in rats |
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| Yang Zhihuan Ying Youguo Li Xiaoyan Weng Gewen Liu Dawei Zhao Min Research Institute of Field Surgery,Third Military Medical College,Chongqing.Effects of ambient pressure on the severity of blast injury in rats[J].Journal of Medical Colleges of PLA(China),1993(4). |
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| Authors: | Yang Zhihuan Ying Youguo Li Xiaoyan Weng Gewen Liu Dawei Zhao Min Research Institute of Field Surgery Third Military Medical College Chongqing |
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| Institution: | Yang Zhihuan Ying Youguo Li Xiaoyan Weng Gewen Liu Dawei Zhao Min Research Institute of Field Surgery,Third Military Medical College,Chongqing 630042 |
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| Abstract: | The effects of different ambient pressures of 53.99,61.33 and 96.60 kPa on the severity of blast injury were observed in rats.It was found that when the incident shock wave was 190.40 kPa in its peak pressure and 10 ms in its duration, both the mortality and the severity of lung injury were progressively increased along with the decrease of the ambient pressure.The mortality rate of the rats in the 6th hour after exposure was 0%,25% and 36.8% and the hem- orrhagic area on the lungs was 63.75+69.01,313.50+357.25 and 653.21+652.25 square milimeters when the ambient pressure was 96.60,61.33 and 53.99 kPa respectively.In addi- tion, the lung/body index was 0.93+0.21%,1.31+0.65% and 1.50+0.77% respectively.It is believed that the decrease of the ambient pressure might decrease the tolerance of the rat to the impact of blast waves to result in higher mortality and more extensive hemorrhage on the lungs. |
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| Keywords: | blast injury ambient pressure mortality injury severity rats |
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