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复方鳖甲软肝片联合恩替卡韦治疗慢性乙型肝炎疗效观察
引用本文:陈茹,郇述玲. 复方鳖甲软肝片联合恩替卡韦治疗慢性乙型肝炎疗效观察[J]. 国际中医中药杂志, 2009, 31(5). DOI: 10.3760/cma.j.issn.1673-4246.2009.05.010
作者姓名:陈茹  郇述玲
作者单位:山东省青岛市传染病医院门诊部,青岛,266033;山东省青岛市传染病医院门诊部,青岛,266033
摘    要:目的 观察复方鳖甲软肝片联合恩替卡韦对慢性乙型肝炎患者肝功能、免疫功能及血清纤维化指标的影响.方法 将168例患者随机分为两组,对照组口服恩替卡韦,治疗组在对照组治疗基础上,加服复方鳖甲软肝片,48周为1个疗程.结果 两组治疗前后肝功能、外周血T淋巴细胞哑群和血清肝纤维化指标比较均有统计学意义(P<0.01或P<0.05),治疗后组间比较治疗组优于对照组(P<0.01或P<0.05).结论 复方鳖甲软肝片联合恩替卡韦治疗慢性乙型肝炎有效.

关 键 词:慢性乙型肝炎  复方鳖甲软肝片  恩替卡韦  联合治疗

Observation on Therapeutic Efficacy of Treating Chronic Hepatitis B with Compound BieJiaRuanGan Pill plus Entacavir
CHEN Ru,HUAN Shu-ling. Observation on Therapeutic Efficacy of Treating Chronic Hepatitis B with Compound BieJiaRuanGan Pill plus Entacavir[J]. International Journal of Traditional Chinese Medicine, 2009, 31(5). DOI: 10.3760/cma.j.issn.1673-4246.2009.05.010
Authors:CHEN Ru  HUAN Shu-ling
Abstract:Objective To observe the therapeutic efficacy of Treating chronic hepatitis B with compound BieJiaRuanGan pill plus entacavir. Methods 168 patients were randomly recruited into a treatment group and a control group. The treatment group was treated with compound BieJiaRuanGan pill plus entacavir and the control group was treated with entacavir exclusively, with a course of 48 weeks. Results Both groups showed statistical significance in improving the liver function, peripheral T lymphocyte subsets and indexes of serum liver fibrosis after the treatment (P<0.01 or P<0.05 ). The therapeutic effects in the treatment group were significant better than the control group after the treatment (P<0.01orP< 0.05 ) . Conclusion The treatment of chronic hepatitis B with compound BieJiaRuanGan pill plus entacavir is better than using entacavir exclusively.
Keywords:Chronic hepatitis B  Compound BieJiaRuanGan pill  Entacavir  Therapeutic alliance
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