Linear Endobronchial Ultrasound as the Initial Diagnostic Tool in Patients With Indications of Mediastinal Disease |
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| Authors: | Ignasi Garcia-Olivé Eduard Xavier Valverde Forcada Felipe Andreo García José Sanz-Santos Eva Castellà Mariona Llatjós Julio Astudillo Eduard Monsó |
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| Affiliation: | 1. Servicio de Neumología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain;2. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain;3. CIBER de Enfermedades Respiratorias (CibeRes), Bunyola, Balearic Islands, Spain;4. Servicio de Anatomía Patológica, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain;5. Servicio de Cirugía Torácica, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain;1. Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA;2. Department of Pathology, Mayo Clinic, Jacksonville, Florida, USA;1. Pathology Department, Hospital del Mar, Barcelona, Spain;2. Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain;3. BIOPAT Biopatologia Molecular, Grup Assistència, Barcelona, Spain;4. Medical Oncology Department, Hospital del Mar, Barcelona, Spain;5. Medical Oncology Department, Consorci Sanitari de Terrassa, Terrassa, Spain;6. Medical Oncology Department, Catalan Institute of Oncology, Hospital Dr. Josep Trueta, Girona, Spain;7. Medical Oncology Department, Hospital Clinic, Barcelona, Spain;8. Pathology Department, Consorci Sanitari de Terrassa, Terrassa, Spain;1. Scottish Centre for Respiratory Medicine, University of Dundee, Dundee, UK;2. Ninewells Hospital and Medical School, University of Dundee, Dundee, UK;1. Department of Thoracic Surgery, National Institute of Diseases of the Chest & Hospital, Dhaka, Bangladesh;2. Department of Thoracic Surgery, National Institute of Diseases of the Chest & Hospital, Dhaka, Bangladesh;3. Department of Thoracic Surgery, National Institute of Diseases of the Chest & Hospital, Dhaka, Bangladesh;4. Khulna Medical College, Khulna, Bangladesh;5. Department of Thoracic Surgery, National Institute of Diseases of the Chest & Hospital, Dhaka, Bangladesh |
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| Abstract: | ![]()
IntroductionLinear endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has proven useful for sampling mediastinal masses and nodes and staging lung cancer. The aim of this study was to assess the usefulness of this diagnostic tool in patients with indications of mediastinal disease that could not be diagnosed by noninvasive methods or white light bronchoscopy.Patients and MethodsAll patients undergoing linear EBUS-TBNA for the diagnosis of mediastinal masses and/or adenopathy at our endoscopy unit were included in the study. Diagnoses obtained by linear EBUSTBNA or any surgical technique performed after a nondiagnostic EBUS-TBNA were considered as final.ResultsIn the study population of 128 patients with a mean (SD) age of 62.0 (11.2) years, a total of 294 TBNAs were performed on 12 masses and 282 nodes. Satisfactory samples were obtained in 11 cases (91.7%) from masses and in 233 cases (82.6%) from nodes. Linear EBUS-TBNA was diagnostic, obviating the need for mediastinoscopy in 115 patients (diagnostic sensitivity, 89.8%). The technique confirmed the diagnosis in 85 of the 94 patients with cancer (90.4%), in 8 of the 10 patients with tuberculosis (80.0%), and in the 5 with sarcoidosis.ConclusionsLinear EBUS-TBNA is a useful diagnostic tool in patients with mediastinal disease for whom a pathologic diagnosis is not achieved by noninvasive methods or white light bronchoscopy. |
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