The role of capsule endoscopy in obscure gastrointestinal bleeding |
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Authors: | Mohamed Serag Zakaria Magdy Amin El-Serafy Iman Mohamed Hamza Khaled Serag Zachariah Tamer Mahmoud El-Baz Jan Bures Ilja Tacheci Stanislav Rejchrt |
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Affiliation: | 1. Duke Clinical Research Institute, Durham, NC, USA;2. University of Oslo, Oslo, Norway;3. Semmelweis University, Hungarian Institute of Cardiology, Budapest, Hungary;4. Methodist DeBakey Heart & Vascular Center, Houston, TX, USA;5. Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand;6. Third Faculty of Medicine, Charles University, Prague, Czech Republic;7. Herzzentrum Ludwigshafen, Ludwigshafen, Germany;8. Brigham and Women''s Hospital, Boston, MA, USA;9. University Hospital of Freiburg, Freiburg, Germany;10. University of Alberta, Edmonton, Canada |
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Abstract: | Background and study aimObscure gastrointestinal bleeding is mostly recurrent and originates in the small bowel, which can be only partially examined by conventional endoscopy. Capsule endoscopy has revolutionized the evaluation of obscure gastrointestinal bleeding (OGIB). The diagnostic yield of capsule endoscopy in OGIB was a main concern of many studies. The aim of this study is to assess the diagnostic yield of capsule endoscopy in cases of OGIB. Capsule-related complications and degree of inter-observer variation will be recorded as well.Patients and methods54 consecutive patients suffering from OGIB, whether occult or overt, were subjected to capsule examination and data analysis.ResultsThe majority (74.1%) presented with obscure overt bleeding. Examination was complete in 68.4%. The commonest lesions were angiodysplasias (17.5%). Examinations were negative for lesions in 35.1% and hampered by limitations in 19.3%. The capsule diagnostic yield was 56.1%, while capsule retention occurred in 3.5%. The inter-observer agreement for the cause of bleeding was 91.2%.ConclusionsCapsule endoscopy proved helpful in solving the mystery of OGIB. It succeeded in diagnosing the cause of bleeding and directing further management with good compliance, high proportion of inter-observer agreement and low incidence of complications. |
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