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| 术中射频消融后病灶刮除治疗脊柱转移瘤 | |
| 引用本文： | 李浩淼,Alessandro,Gasbarrini,Michele,Cappuccio,Rakesh,Donthineni,Lu,Boriani,Stefano,Bandier,Laur,Foroni,Gianandre,Pasquinelli,Stefano,Boriani. 术中射频消融后病灶刮除治疗脊柱转移瘤[J]. 中国脊柱脊髓杂志, 2008, 18(11) |
| 作者姓名： | 李浩淼 Alessandro Gasbarrini Michele Cappuccio Rakesh Donthineni Lu Boriani Stefano Bandier Laur Foroni Gianandre Pasquinelli Stefano Boriani |
| 作者单位： | 1. 中山大学附属第一医院黄埔院区脊柱外科,510700,广东省广州市 2. 博洛尼亚lVlaggiore医院骨创伤与脊柱外科,40100,意大利 3. 博洛尼亚大学S.Orsoh-Malpi出医院外科与麻醉专科,40138,意大利 4. 博洛尼亚大学S.Omoh-Malpighi实验病理科临床病理组,40138,意大利 |
| 摘 要： | 目的:探讨术中射频消融(RFA)后再行病灶刮除术治疗脊柱转移瘤的可行性及疗效.方法:2004年～2006年,对11例脊柱转移瘤患者术中实施RFA后再行病灶刮除术,将FRA前后病灶标本进行光镜和电镜病理检查,随访患者疼痛缓解情况及肿瘤复发情况.结果:术中未出现脊髓和神经根损伤,RFA后瘤组织固缩,刮除顺利,出血量350～3800ml,平均1024.5ml.全部病例得到6个月以上随访,平均9.8个月,全部患者生存期超过6个月,VAS评分术前平均5.8分,术后6个月时平均1.9分.1例出现局部肿瘤复发.RFA前的标本光、电镜检查均未见肿瘤组织坏死.RFA后光镜检查3例无明显坏死,9例肿瘤细胞完全坏死:电镜检查10例肿瘤细胞完全坏死,1例肿瘤细胞部分坏死,1例无明显坏死.结论:术中RFA后再行病灶刮除治疗脊柱转移瘤安全可行,有利于肿瘤的刮除,减少局部复发的风险. |
| 关 键 词： | 骨转移瘤 脊柱 外科治疗 射频 消融术 |
Treatment of spinal metastases by curettage combined with introperative radiofrequency ablation: a report of 11 cases |
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| Alessandro Gasbarrini,Michele Cappuccio,Stefano Bandier,Luca Boriani,Gianandrea Pasquinelli,Stefano Boriani,Gianandrea Pasquinelli,Stefano Boriani,LI Haomiao,Alessandro Gasbarrini,Michele Cappuccio,Stefano Bandier,Luca Boriani,Gianandrea Pasquinelli,Ste. Treatment of spinal metastases by curettage combined with introperative radiofrequency ablation: a report of 11 cases[J]. Chinese Journal of Spine and Spinal Cord, 2008, 18(11) | |
| Authors: | Alessandro Gasbarrini Michele Cappuccio Stefano Bandier Luca Boriani Gianandrea Pasquinelli Stefano Boriani Gianandrea Pasquinelli Stefano Boriani LI Haomiao Alessandro Gasbarrini Michele Cappuccio Stefano Bandier Luca Boriani Gianandrea Pasquinelli Ste |
| Affiliation: | LI Haomiao,Aless,ro Gasbarrini,Michele Cappuccio,et al Department of Spine Surgery,Huangpu Branch of the First Affiliated Hospital of Sun Yat-sen University,Guangzhou,510700,China |
| Abstract: | Objective:To explore the possibility and effect of clinical treatment of spinal metastases by curettage combined with introperative radiofrequency ablation(RFA).Method:During 2004 to 2006,11 patients with spinal metastases had undergone treatment of curettage combined with introperative RFA.Clinical observations for the patients as well as the pathologic examinations for the introperative samples before and after RFA un-der both light microscope and electron microscope were performed.Result:There were no in... |
| Keywords: | Bone metastasis Spine Surgical treatment Radiofrequency Ablation |
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