慢性嗜酸粒细胞肺炎的研究进展

慢性嗜酸粒细胞肺炎是一种病因不明的慢性肺嗜酸粒细胞性炎症,临床表现无特异性,其特点为周围性肺浸润影;外周血和(或)支气管肺泡灌洗液中嗜酸粒细胞数显著增高;抗感染治疗无效而对糖皮质激素的反应良好,但在减量或停用糖皮质激素时容易复发.

Research progress of chronic eosinophilic pneumonia

Chronic eosinophilic pneumonia (CEP) is a rare disease of unknown cause marked by eosinophilic infiltration of the lungs, with nonspecific respiratory and systemic symptoms which are characterized by peripheral pulmonary infiltrates on chest imaging. Blood and/or bronchoalveolar lavage fluid in CEP always demonstrates high levels of eosinophils. Antibiotic treatment is ineffective in CEP while its dramatic responds to corticosteroid therapy, but relapses are frequent on reduction or cease of the corticosteroid treatment.