| Azimexon对小鼠脾细胞增殖以及产生白细胞介素2的影响 |
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| 引用本文： | 宋锦平,钱定华,徐炳祥.Azimexon对小鼠脾细胞增殖以及产生白细胞介素2的影响[J].第二军医大学学报,1988(1). |
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| 作者姓名： | 宋锦平 钱定华 徐炳祥 |
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| 作者单位： | 第二军医大学药学系药理教研室
(宋锦平，钱定华)，第二军医大学药学系中西药研究室(徐炳祥) |
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| 摘 要： | 在体外试验中研究了azimexon对小鼠脾细胞增殖以及白细胞介素2(IL-2)的影响。IL-2活性采用小鼠胸腺细胞增殖法和CTLL细胞增殖法测定。结果表明:azimexon单独不能增加脾细胞增殖和产生IL-2,但对亚适量ConA或LPS诱导的脾细胞增殖和产生IL-2有明显协同作用。
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| 关 键 词： | azimexon 淋巴细胞增殖 白细胞介素2 |
EFFECTS OF AZIMEXON ON MURINE SPLENOCYTE PROLIFERATION AND INTERLEUKIN-2 PRODUCTION |
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| Song Jinping,et al.EFFECTS OF AZIMEXON ON MURINE SPLENOCYTE PROLIFERATION AND INTERLEUKIN-2 PRODUCTION[J].Academic Journal of Second Military Medical University,1988(1). |
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| Authors: | Song Jinping |
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| Abstract: | In this paper, we studied the effects of azimexon on murine splenocyte proliferation and interlcukin-2(IL-2)production.IL-2 activity was detected by means of two method-murine thymocyte proliferation assay and CTLL2 proliferation assay,The results show that azimexon alone did not increase splenocyte proliferation and IL-2 production.But azimexon could markedly promote the proliferation and IL-2 production of splenocytes induced by ConA or LPS at a subopti-mal dose. |
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| Keywords: | azimexon proliferation of lymphocytes interleukin-2 |
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