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| 脊髓亚急性联合变性临床特点研究 | |
| 引用本文： | 郭晓玲,黄旭升,刘淑贤,陈朝晖. 脊髓亚急性联合变性临床特点研究[J]. 中国神经免疫学和神经病学杂志, 2011, 18(2): 83-86. DOI: 10.3969/j.issn.1006-2963.2011.02.003 |
| 作者姓名： | 郭晓玲 黄旭升 刘淑贤 陈朝晖 |
| 作者单位： | 1. 河北省承德市解放军第二六六医院神经内科,067000 2. 解放军总医院神经内科,100850 |
| 摘 要： | 目的研究脊髓亚急性联合变性(SCD)的临床、电生理及MRI特点,评价电生理及MRI在该病诊断中的价值。方法回顾性收集56例临床确诊SCD患者的临床资料,其中52例行血清维生素B12及叶酸水平测定,31例行血清同型半胱氨酸(Hcy)水平测定,56例均行针极肌电图、胫神经体感诱发电位(SEP)检查,其中29例行视觉诱发电位(VEP)及22例听觉诱发电位(BAEP)检查,51例根据临床定位行MRI检查。结果 52例中35例血清维生素B12水平、14例叶酸水平低于正常范围;31例中12例血清Hcy水平高于正常范围。56例肌电图检查结果均正常;56例中运动神经传导异常51根(45例),感觉神经传导异常90根(56例),胫神经SEP异常83侧(56例);29例中VEP结果异常22侧(12例),BAEP结果异常9侧(7例)。51例中23例可见脊髓不同范围长T2信号,8例可见单纯后索长T2信号,8例可见后索合并侧索长T2信号。结论诊断SCD应综合临床表现及实验室检查结果,神经电生理及MRI检查对判断SCD病变部位及评价治疗前后病情变化具有一定价值。 |
| 关 键 词： | 脊髓亚急性联合变性 维生素B12缺乏 神经电生理 |
A study of clinical, electrophysiological and neuropathological characteristics of subacute combined degeneration of the spinal cord |
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| GUO Xiao-ling,HUANG Xu-sheng,LIU Shu-xian,CHEN Zhao-hui. A study of clinical, electrophysiological and neuropathological characteristics of subacute combined degeneration of the spinal cord[J]. Chinese Journal of Neuroimmunology and Neurology, 2011, 18(2): 83-86. DOI: 10.3969/j.issn.1006-2963.2011.02.003 | |
| Authors: | GUO Xiao-ling HUANG Xu-sheng LIU Shu-xian CHEN Zhao-hui |
| Affiliation: | GUO Xiao-ling,HUANG Xu-sheng,LIU Shu-xian,CHEN Zhao-hui.Department of Neurology,266 Hospital of PLA,Chengde Hebei 067000,China |
| Abstract: | Objective To analyze the clinical manifestations,electrophysiological features and MRI findings of patients with subacute combined degeneration of the spinal cord(SCD),and to evaluate the diagnostic values of electrophysiology and MRI in SCD.Methods 56 SCD patients were retrospectively reviewed.Among them,the serum levels of vitamin B12 and folate acid(FA) in 52 cases and the serum level of homocysteine(Hcy) in 31 cases were measured.All of them underwent electromyogram and somatosensory evoked potentials(S... |
| Keywords: | subacute combined degeneration vitamin B12 deficiency neuroelectrophysiology |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |