Paraneoplastic movement disorder in a patient with non-Hodgkin's lymphoma and CRMP-5 autoantibody. |
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Authors: | Ali Samii Debra D Dahlen Alexander M Spence Nicole C Maronian Eric E Kraus Vanda A Lennon |
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Affiliation: | Department of Neurology, University of Washington School of Medicine, Seattle, Washington, USA. asamii@u.washington.edu |
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Abstract: | The paraneoplastic autoantibody, collapsin response-mediator protein (CRMP)-5 immunoglobulin G (IgG), is specific for neuronal cytoplasmic CRMP-5, and is usually associated with small-cell lung carcinoma or thymoma. We report on details of a movement disorder that followed anti-B-cell therapy in a patient with lymphoma, and was accompanied by CRMP-5 IgG. |
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Keywords: | chorea dystonia B‐cell lymphoma autoimmunity rituximab |
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