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Correction of the pathogenic mutation in TGM1 gene by adenine base editing in mutant embryos
Institution:1. Department of Obstetrics and Gynecology, Center of Reproductive Medicine, Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China;2. Key Laboratory for Reproductive Medicine of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China;3. Department of Reproductive Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;4. Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China
Abstract:
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  • Keywords:correction  pathogenic mutation  adenine base editing  mutant embryos
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