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多模板分子印迹固相萃取及其在中药多组分提取分离中的应用
引用本文:李硕,常月月,程芳芳,包贝华,曹雨诞,姚卫峰,张丽,丁安伟. 多模板分子印迹固相萃取及其在中药多组分提取分离中的应用[J]. 药学学报, 2021, 0(3): 751-760
作者姓名:李硕  常月月  程芳芳  包贝华  曹雨诞  姚卫峰  张丽  丁安伟
作者单位:南京中医药大学药学院
基金项目:国家自然科学基金面上资助项目(81973445)。
摘    要:多模板分子印迹固相萃取不仅具有高选择性、吸附容量大、容易制备、可重复使用以及环境污染小等优点,而且可以实现对多种化合物的富集分离,在中药成分提取分离方面受到广泛的关注.本研究总结归纳了多模板分子印迹固相萃取的最新发展,同时基于中药活性成分的种类(黄酮、生物碱、苯丙素和萜类等)分类综述多模板分子印迹固相萃取在中药多组分分...

关 键 词:多模板  分子印迹  固相萃取  中药多组分  提取分离

Multi-template molecularly imprinted solid phase extraction and its application in the extraction and separation of multi-components from traditional Chinese medicine
LI Shuo,CHANG Yue-yue,CHENG Fang-fang,BAO Bei-hua,CAO Yu-dan,YAO Wei-feng,ZHANG Li,DING An-wei. Multi-template molecularly imprinted solid phase extraction and its application in the extraction and separation of multi-components from traditional Chinese medicine[J]. Acta pharmaceutica Sinica, 2021, 0(3): 751-760
Authors:LI Shuo  CHANG Yue-yue  CHENG Fang-fang  BAO Bei-hua  CAO Yu-dan  YAO Wei-feng  ZHANG Li  DING An-wei
Affiliation:(School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China)
Abstract:Multi-template molecularly imprinted solid phase extraction not only has the advantages of high selectivity, large adsorption capacity, easy preparation, reuse and low environmental pollution, but also can realize the enrichment and separation of many kinds of compounds. It has attracted wide attention in the extraction and separation of traditional Chinese medicine components. This study summarizes the latest development of multitemplate molecularly imprinted solid phase extraction. At the same time, based on the classification of active components of traditional Chinese medicine(flavonoids, alkaloids, phenylpropanol, terpenes, etc.), the latest application of multi-template molecular imprinting solid phase extraction in multi-component separation of traditional Chinese medicine was reviewed, with a view to better application of multi-template molecularly imprinted polymer in active multi-component extraction and separation of traditional Chinese medicine and provide reference for the material basic research of the efficacy of traditional Chinese medicine.
Keywords:multi-template  molecular imprinting  solid phase extraction  multi-component of traditional Chinese medicine  extraction and separation
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