包装材料及装载方式对低温灭菌后过氧化氢吸附程度的影响

目的:探讨在低温等离子灭菌时,无纺布与特卫强两种包装材料的不同装载方式对过氧化氢吸附程度及注射期压力的影响。方法:2019年4—6月,在郑州大学第一附属医院消毒供应中心,将6个空硅树脂器械盒分为2种包装方式,3个采用100 cm 2的无纺布双层包装,3个采用60 cm× 20 cm的特卫强纸塑袋单层包装。对...

Effects of packaging materials and loading modes on the degree of hydrogen peroxide adsorption after low-temperature sterilization

Objective To explore effects of different loading modes of non-woven fabric and Tyvek packaging materials on degree of hydrogen peroxide adsorption and pressure during injection during low temperature plasma sterilization.Methods From April to June 2019,6 empty silicone resin instrument boxes were divided into two packaging methods in Disinfectant Supply Center of the First Affiliated Hospital of Zhengzhou University,3 of which were double-packed with 100 cm2 non-woven fabric and 3 of which were single-packed with 60 cm×20 cm Tvek paper-plastic bags.In the control group,the 3 non-woven packages to be sterilized were placed on the upper shelf of the sterilizer,and the 3 Tyvek packages to be sterilized were placed on the lower shelf.The loading order of the experimental group was reversed.The three packages of Tyvek packaging to be sterilized were placed on the upper shelf,and the three packages of non-woven packaging were placed on the lower shelf.The loading capacity of the two methods was 70%,and 20 times of sterilization were respectively carried out according to the normal process.The concentration of hydrogen peroxide adsorbed by the sterile bags was detected immediately after sterilization,and the pressure during each injection period was recorded.Results The adsorption concentrations of hydrogen peroxide in sterile packages of non-woven fabric and Tevek in the experimental group were respectively(11.120±4.187)ppm and(8.205±4.181)ppm,and the difference was statistically significant(t=2.203,P<0.05).The adsorption concentrations of hydrogen peroxide of the two packaging materials in the control group were respectively(13.745±3.754)ppm and(8.065±4.599)ppm,and the difference was statistically significant(t=4.279,P<0.01).The difference in the adsorption concentration of non-woven fabrics between the two groups was statistically significant(t=2.088,P<0.05).There was no statistically significant difference in the adsorption of Tyvek between the two groups(t=0.164,P>0.05).The pressure during injection of the experimental group was(9.410±0.188)Torr,and that of the control group was(9.121±0.243)Torr,and the difference was statistically significant(t=4.215,P<0.01).Conclusions When low temperature plasma sterilization of hydrogen peroxide is carried out,Tyvek packaging has adsorption of weak hydrogen peroxide,so it is more suitable for sterilization.In the mixed loading,the sterilization packages packed with Tyvek and non-woven fabric are respectively placed on the upper and lower layers,which can reduce the adsorption amount of hydrogen peroxide of packaging materials,improve the pressure during the injection period of sterilization and ensure the sterilization quality.