中药面膜联合阿达帕林凝胶治疗寻常痤疮的临床观察

目的：评价中药面膜联合0．1％阿达帕林凝胶治疗轻、中度寻常痤疮的临床疗效及安全性。方法寻常痤疮76例，随机分为两组，治疗组40例，采用中药面膜联合0．1％阿达帕林凝胶治疗；对照组36例，单独使用0．1％阿达帕林凝胶治疗。两组均在治疗6周后观察疗效并评价安全性。结果试验组、对照组的总有效率在第6周时分别为82．5％和52．7％，具有明显的差异。在治疗过程中，两组均未见明显不良反应。结论中药面膜联合0．1％阿达帕林凝胶治疗轻、中度寻常痤疮较单用阿达帕林疗效显著，见效快，病程短，无明显不良反应。

Clinical therapeutic effect of herbal facial mask combined with adapalene gel in treatment of acne vulgaris

Objective To evaluate the clinical efficacy and safety of the combination therapy of herbal facial mask with 0.1%adapalene gel in patients with mild and moderate acne vulgaris .Methods A total of 76 patients with mild to moderate acne vulgaris were enrolled and randomly divided into 2 groups：40 cases in treatment group which were treated by herbal facial mask combined with 0.1%adapalene gel;36 cases in control group which were treated only by 0.1%adapalene gel .All the patients received therapy for 6 weeks continuously and had been observed to evaluate the efficacy and safety on the sixth week of treatment .Results On the sixth week of treatment, the total effective rate of treatment group was 82.5%, and there was a significant difference compared with the control group （ 52.7%） .All these 2 groups had not obvious side-effect during treatment . Conclusions Herbal facial mask combined with 0.1% adapalene gel therapy is more effective than adapalene monotherapy in mild to moderate acne cases with a rapid response and similar adverse reactions .