| 喉鳞癌间质血管生成和淋巴结转移的相关性 |
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| 引用本文： | 韩英杰,李玉林,张丽红. 喉鳞癌间质血管生成和淋巴结转移的相关性[J]. 天津医科大学学报, 2001, 7(1): 24-26 |
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| 作者姓名： | 韩英杰 李玉林 张丽红 |
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| 作者单位： | 1. 天津医科大学病理教研室,
2. 白求恩医科大学病理教研室 |
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| 摘 要： | 目的：观察喉鳞癌间质血管的形态特点，探讨喉鳞癌间质血管密度（MVD）与其临床病理特征的关系，方法：应用免疫组织化学LSAB法和形态计量技术，对36例临床资料完整 的喉鳞癌组织间质血管的内皮细胞和基底膜的主要成分进行标记，并统计单位面积内微血管数，结果：喉鳞癌间质血管分布存在异质性，且多数为新生的毛细血管样血管，基底膜不完整甚至缺如，有淋巴结转移的喉鳞癌，其间质微血管密度明显高于无淋巴结转移者（P＜0．05），结论：喉鳞癌间质微血管密度可作为判定喉鳞癌转称倾向的有用指标之一。
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| 关 键 词： | 喉鳞癌 微血管密度 淋巴结转移 |
| 文章编号： | 1006-8147(2001)01-0024-03 |
| 修稿时间： | 2000-04-11 |
Angiogenisis amd itscorrelation with lymphatic metastasis in laryngocarcinoma |
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| HAN Ying-jie,LI Yu-Lin,ZHANG Li-Hong. Angiogenisis amd itscorrelation with lymphatic metastasis in laryngocarcinoma[J]. Journal of Tianjin Medical University, 2001, 7(1): 24-26 |
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| Authors: | HAN Ying-jie LI Yu-Lin ZHANG Li-Hong |
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| Affiliation: | HAN Ying-Jie1,LI Yu-Lin2,ZHANG Li-Hong2 |
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| Abstract: | Objective:To observe the pathologic features and distribution of stroma bloodvessels in laryngocarcinoma,to investigate the relationship between microvasscular density(MVD)and pathologic characters in laryngocarcinoma. Methods: Immunohistochemical assays and quantative analysis were used in 36 cases of laryngocarcinoma. Results: Most of stroma bloodvessels are neogenesic capilary-like microvessels and vascular buds,and the distribution of stroma bloodvessels is uneven.The MVD of laryngocarcinoma with lymphatic metastasis is significantly higher than that without lymphatic metastasis(P<0.05). Conclusion: MVD may be a novel morphological marker for determining the tendency of lymphamatic metastasis in laryngocarcinoma. |
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| Keywords: | Laryngocarcinoma Angiogenesis Lymphatic metastasis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
