| S100B与缺血性卒中关系的研究进展 |
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| 引用本文： | 李慧,梁庆成. S100B与缺血性卒中关系的研究进展[J]. 中国卒中杂志, 2012, 7(5): 430-433 |
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| 作者姓名： | 李慧 梁庆成 |
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| 作者单位： | 哈尔滨医科大学附属第二医院神经内科 |
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| 摘 要： | 缺血性卒中仍是当今社会威胁健康的主要疾病，它是我国引起死亡以及残疾的重要原因。S100B是与神经系统紧密相关的蛋白，它在缺血性卒中过程中可以发挥神经毒作用，诱导神经元以及星形胶质细胞凋亡。临床试验发现，S100B的水平与缺血性卒中患者病灶面积大小和预后有关。由于S100B在中枢神经系统的生物学特性，提示它可能在将来作为一项诊断卒中的生物标记物。
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| 关 键 词： | S100B蛋白 缺血性卒中 |
| 收稿时间： | 2011-10-21 |
Research Progress of the Relation of SIOOB and Ischemic Stroke |
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| LI Hui , LIANG Qing-Cheng. Research Progress of the Relation of SIOOB and Ischemic Stroke[J]. Chinese Journal of Stroke, 2012, 7(5): 430-433 |
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| Authors: | LI Hui LIANG Qing-Cheng |
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| Affiliation: | . Department of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China |
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| Abstract: | Stroke remains a significant public health burden and the leading cause of death and disability of our country. S 100B is a protein relevant with the nervous system; it can induce the cell apoptosis of neuron and astrocytes during stroke. In clinical trials, S 100B is related to the volume of infarcted tissue and functional outcome of stroke. The biological characteristics of S100B suggest that it can be used as a biomarker of stroke. |
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| Keywords: | S100B Ischemic stroke |
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