老年人非甾体类抗炎药致消化道出血患者的临床特征观察

目的：分析老年人非甾体类抗炎药（NSAIDs）致消化道出血临床特征。方法方便选取从2014年1月—2016年1月收治的100例NSAIDs致消化道出血患者,根据年龄分为中青年组（50例）与老年组（50例）,观察两组血红蛋白（Hb）、凝血酶时间（TT）、活化部分凝血活酶时间（APTT）、凝血酶原时间（PT）、纤维蛋白原（Fg）、血小板数量（PLT）等指标,分析其临床特征。结果老年组中,28例应用NSAIDs（主要为阿司匹林）,占56.00%,明显高于中青年组36.00%（P<0.05）。老年组中,应用NSAIDs一周后,11例发生上消化道出血（22.00%）,低于中青年组60.00%（P<0.05）羌率有统计学意义（P<0.05）。结论与中青年相比,老年人NSAIDs致消化道出血临床特征存在一定差异,需采取个体化治疗。

Clinical Characteristics of Elderly Patients with Gastrointestinal Bleeding Induced by Non Steroidal Anti-inflammatory Drugs

Objective To analyze the older non-steroidal anti-inflammatory drugs (NSAIDs) induced gastrointestinal bleed-ing clinical features.Methods Convenient selected from January 2014 to January 2016 100 cases of NSAIDs induced gas-trointestinal bleeding, according to the age in young group (50) and the elderly group (50) were observed in two groups of hemoglobin (HB), thrombin time (TT), activation activated partial thromboplastin time (APTT), prothrombin time (PT), fib-rinogen (FG), platelet count (PLT) index, analysis the clinical features.Results The elderly group and 28 patients were treated with NSAIDs (mainly aspirin), accounting for 56.00%, significantly higher than the young group 36.00% (P<0.05). Elderly group, after applying NSAIDs week 11 cases of gastrointestinal bleeding (22.00%), lower than the young group 60.00% (P<0.05)The differenre wes statistically significant (P<0.05). Conclusion Compared with the young, the elderly, the clinical features of gastrointestinal bleeding caused by NSAIDs there are some differences, need to take individualized treatment.