首页 | 本学科首页   官方微博 | 高级检索  
     

分析奥沙利铂联合氟脲嘧啶治疗晚期胃肠肿瘤的临床疗效
引用本文:崔艳艳. 分析奥沙利铂联合氟脲嘧啶治疗晚期胃肠肿瘤的临床疗效[J]. 中外医疗, 2016, 0(28): 128-130. DOI: 10.16662/j.cnki.1674-0742.2016.28.128
作者姓名:崔艳艳
作者单位:内蒙古赤峰学院附属医院肿瘤内科,内蒙古赤峰,024000
摘    要:目的:对奥沙利铂联合氟脲嘧啶治疗胃肠肿瘤的临床疗效及不良反应进行探讨。方法回顾性分析该院2013年2月—2016年1月收治的110例胃肠恶性肿瘤患者,110例胃肠恶性肿瘤患者均给予奥沙利铂联合氟脲嘧啶方案治疗,并观察给予奥沙利铂联合氟脲嘧啶方案治疗胃肠恶性肿瘤的临床疗效及不良反应。结果胃肠恶性肿瘤患者在接受奥沙利铂联合氟脲嘧啶方案治疗后的总有效率为80.90%,不良反应发生率为10.91%,其中2例患者发生肾功能损伤,3例患者发生胃肠道不适,外周神经病变患者3例及手足综合征患者4例。结论给予胃肠肿瘤患者奥沙利铂联合氟尿嘧啶进行治疗的效果确切,并且不良反应较少,值得用于胃肠道肿瘤类治疗。

关 键 词:氟脲嘧啶  奥沙利铂  临床疗效  不良反应

Analysis of Oxaliplatin Combined with Fluorouracil Clinical Efficacy in Pa-tients with Advanced Gastrointestinal Cancer
Abstract:Objective To oxaliplatin combined with fluorouracil treatment of gastrointestinal cancer clinical efficacy and side effects were observed. Methods A retrospective analysis of our hospital from February 2013 to January 2016 were treated 110 cases of gastrointestinal cancer patients, 110 cases of gastrointestinal cancer patients were treated with oxali-platin combined with fluorouracil regimen, and was observed by the oxaliplatin combined with fluorouracil in the treatment of gastrointestinal tumors access clinical efficacy and adverse reactions. Results The disease control rate in gastrointestinal cancer patients receiving oxaliplatin combined probability fluorouracil regimen was 80.90% and 10.91% incidence of ad-verse reactions, including 2 patient with renal impairment, 3 patient Stomach gastrointestinal discomfort, peripheral neuropa-thy in 3 patients and hand-foot syndrome in 4 patient. Conclusion The administration of gastrointestinal cancer patients oxaliplatin combined with fluorouracil for treatment of the exact effect, and fewer adverse reactions, it is worth for the treat-ment of gastrointestinal cancer type.
Keywords:Fluorouracil  Oxaliplatin  Clinical efficacy  Adverse reactions
本文献已被 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号