干眼检查中泪膜破裂时间测定对泪河高度的影响

目的：研究在进行泪河高度(TMH)测量时非侵入性泪膜破裂时间测定(NIK-BUT)对其的影响。方法整群选取2015年3月—2015年6月在厦门市中医院眼科就诊的63例干眼患者及63名常规体检的健康人，所有入选者都用Keratograph 5M眼表综合分析仪(OCULUS，德国)拍摄泪河的图片，记录基础泪河高度(△TMH)，并在非侵入性泪膜破裂时间检查前后分别测量泪河高度。泪膜破裂时间检查要求受检者尽量保持不眨眼，并在下一次眨眼后停止检查。结果健康人群及干眼患者的基础TMH(△TMH)分别为(0.24±0.06) mm和(0.14±0.04) mm。干眼患者基础TMH值显著低于健康人群TMH(P<0.001)。在行NIK-BUT检查后TMH值显著增加，健康人群TMH增加(0.12±0.08)mm，干眼患者TMH增加(0.06±0.09)mm(P<0.001,P=0.026)。结论在用眼表综合分析仪检测干眼患者时，泪河高度测量应该在泪膜破裂时间检查等强制性眨眼动作前完成。

Dry Eye Examination in the Tear Film Break-up Time of Tears River Height Determination

Objective To study the effect of non-invasive break-up time (NIK-BUT) measurement on tear meniscus height (TMH) assessment. Methods Group selection 63 patients with dry eye and 63 normal subjects who treated in Xiamen Hos-pital of TCM from March 2015 to June 2015 were enrolled.Lower tear meniscus images were captured, the baseline TMH (△TMH) was measured,and then recorded TMH values before and after NIK-BUT measurements in each subject with Ker-atograph 5M(OCULUS,Germany). NIK-BUT measurements need all subjects to keep their eyes open as long as possible un-til the next blink. Results The△TMH values of the normal and dry eye groups were (0.24±0.06)mm and (0.14±0.04)mm. The △TMH values of dry eye patients were significantly lower than normal subjects (P<0.001). Significant increases in TMH values were observed in both normal subjects (0.12±0.08)mm and dry eye patients(0.06±0.09)mm after NIK-BUT mea-surement (P<0.001, P=0.026). Conclusion On the diagnosis of dry eye with Keratograph 5M,TMH should be assessed before tests that require forced eye opening such as NIK-BUT.