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| HER2／neu在胃癌中的研究进展 | |
| 引用本文： | 崔小伟,张庆瑜. HER2／neu在胃癌中的研究进展[J]. 国际消化病杂志, 2008, 28(4) |
| 作者姓名： | 崔小伟 张庆瑜 |
| 作者单位： | 300052天津医科大学总医院消化内科 |
| 摘 要： | HER2/neu与多种肿瘤的发生、发展关系密切。它通过下游的信号转导途径参与肿瘤细胞的增殖、凋亡、浸润与侵袭等基因的调控。HER2/neu在胃癌中存在高表达或基因扩增现象,并可能影响胃癌患者的预后,也可能参与了胃癌肝转移过程。HER2/neu有望成为胃癌治疗的一个新靶点。 |
| 关 键 词： | HER2/neu 胃癌 基因调控 |
Research development of HER2/neu in gastric cancer |
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| CUI Xiao-wei,ZHANG Qing-yu. Research development of HER2/neu in gastric cancer[J]. International Journal of Digestive Disease, 2008, 28(4) | |
| Authors: | CUI Xiao-wei ZHANG Qing-yu |
| Abstract: | HER2/neu plays an important role in the development of many tumors.HER2/neu participates the gene regulation of cell proliferation,apoptosis and invasion.HER2/neu indicates over-expression or gene proliferation in gastric cancer,and probably influences the outcomes of patients with gastric cancer,and participates hepatic metastasis progression of gastric cancer.HER2/neu may become a new therapy target of gastric cancer. |
| Keywords: | HER2/neu Gastric cancer Gene regulation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |