| CD44在肿瘤进展中的作用 |
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| 引用本文： | 李丹华,张斌,曹旭晨. CD44在肿瘤进展中的作用[J]. 国际肿瘤学杂志, 2013, 40(1): 18-21 |
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| 作者姓名： | 李丹华 张斌 曹旭晨 |
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| 作者单位： | 李丹华 (300060,天津医科大学附属肿瘤医院乳腺一科乳腺癌防治教育部重点实验室 天津市肿瘤防治重点实验室); 张斌 (300060,天津医科大学附属肿瘤医院乳腺一科乳腺癌防治教育部重点实验室 天津市肿瘤防治重点实验室); 曹旭晨 (300060,天津医科大学附属肿瘤医院乳腺一科乳腺癌防治教育部重点实验室 天津市肿瘤防治重点实验室); |
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| 摘 要： |
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Effects of CD44 in cancer progression |
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| Affiliation: | First Department of Breast Oncology, Affiliated Cancer Hospital of Tianjin Medical University; Key Laboratory of Breast Cancer Prevention and Treatment of Ministry of Education; Key Laboratory of Cancer Prevention and Treatment of Tianjin, Tianjin 300060, China |
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| Abstract: | CD44 has been the subject of extensive research because of its role in cancer and many physiological processes. Through binding to different ligands, CD44 can initiate a series of cascade. CD44 not only can promote tumorigenic and tumor metastasis, but also can suppress tumor growth and progression. In-depth study of CD44 and its role in signal pathway may provide a new path for cancer treatment. |
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| Keywords: | CD44 Neoplasm metastasis Prognosis |
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