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Doxycycline vs. macrolides in combination therapy for treatment of community-acquired pneumonia
Authors:Teh B  Grayson M L  Johnson P D R  Charles P G P
Affiliation:Department of Infectious Diseases, Austin Health, Heidelberg, Vic., Australia.
Abstract:
We assessed the comparative efficacy of empirical therapy with beta-lactam plus macrolide vs. beta-lactam plus doxycycline for the treatment of community-acquired pneumonia (CAP) among patients in the Australian Community-Acquired Pneumonia Study. Both regimens demonstrated similar outcomes against CAP due to either 'atypical' (Chlamydophila, Legionella or Mycoplasma spp.) or typical bacterial pathogens.
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