| 溪黄草提取物抗脂质过氧化作用研究 |
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| 引用本文： | 段志芳,黄晓伟.溪黄草提取物抗脂质过氧化作用研究[J].西北药学杂志,2008,23(2):93-94. |
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| 作者姓名： | 段志芳 黄晓伟 |
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| 作者单位： | 广东肇庆学院生物医药工程中心,广东,肇庆,526061 |
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| 摘 要： | 目的研究溪黄草提取物抗脂质过氧化作用。方法采用组织匀浆MDA比色法测定不同质量浓度溪黄草水提取物及乙醇提取物对SD大鼠离体肾脏、肝脏、心脏、脾脏和肺脏组织脂质过氧化的影响。结果2种提取物均具有明显的抗脂质过氧化活性,其中水提取物活性大于乙醇提取物,在1.00g.L-1质量浓度时,水提取物对SD大鼠离体组织MDA的抑制率大小为:肾脏>肝脏>心脏>脾脏>肺脏。结论溪黄草水提取物及乙醇提取物具有抗脂质过氧化作用。
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| 关 键 词： | 溪黄草 提取物 MDA 抗氧化作用 |
| 文章编号： | 1004-2407(2008)02-0093-02 |
| 修稿时间： | 2007年5月18日 |
Study on anti-lipid peroxidation effects of the extracts from Rabdosia serra(Maxim.)Hara on tissue homogenate of mice |
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| DUAN Zhifang,HUANG Xiaowei.Study on anti-lipid peroxidation effects of the extracts from Rabdosia serra(Maxim.)Hara on tissue homogenate of mice[J].Northwest Pharmaceutical Journal,2008,23(2):93-94. |
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| Authors: | DUAN Zhifang HUANG Xiaowei |
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| Abstract: | Objective To investigate the anti-lipid peroxidation effects of the extracts from Rabdosia serra(Maxim.)Hara.Methods Rabdosia serra(Maxim.)Hara was extracted by water and ethanol.The effects of the water and ethanol extracts on anti-lipid peroxidation were tested by tissue homogenate MDA of mice.Results The experiments showed that the extracts had obvious effects of antioxidations with dose-effect relationship on kidney,liver,heart,spleen and lung.The anti-lipid peroxidation activity of the water extract was higher than that of the ethanol extract.When the concentration of the water extract was 1.00 g·L-1,it was found that the effect was kidney > liver > heart > spleen > lung by comparison with the inhibitory rate of tissue homogenate MDA.Conclusion The water and ethanol extracts from Rabdosia serra(Maxim.)Hara have remarkable effects on anti-lipid peroxidation. |
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| Keywords: | Rabdosia serra(Maxim )Hara extract MDA antioxidation |
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