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Performance characteristics of 10 home mechanical ventilators in pressure-support mode: a comparative bench study
Authors:Battisti Anne  Tassaux Didier  Janssens Jean-Paul  Michotte Jean-Bernard  Jaber Samir  Jolliet Philippe
Affiliation:1. Departments of Medical Intensive Care, Hoôpital Cantonal Universitaire, Geneva, Switzerland;2. Pneumology, Hoôpital Cantonal Universitaire, Geneva, Switzerland;3. Physiotherapy, Hoôpital Cantonal Universitaire, Geneva, Switzerland;4. Department of Anesthesia and Intensive Care, Centre Hospitalier Universitaire, Montpellier, France;1. Service de Réanimation Médicale, Hôpital Européen Georges-Pompidou, Assistance Publique–Hôpitaux de Paris, Paris, France;2. Université Paris Descartes, Faculté de Médecine, Paris, France;3. Service de Gériatrie, Hôpital Européen Georges-Pompidou, Assistance Publique–Hôpitaux de Paris, Paris, France;4. UF Hygiène Hospitalière, Hôpital Européen Georges-Pompidou, Assistance Publique–Hôpitaux de Paris, Paris, France;1. Clinique des Bronches, Allergies et du Sommeil, Assistance Publique Hôpitaux de Marseille, France et INSERM U1067, CNRS UMR 7333 Aix Marseille Université, France;2. Département de Pneumologie, Hôpital Arnaud de Villeneuve, CHRU de Montpellier, 371 Avenue du Doyen Giraud, 34295 Montpellier Cedex 5, France;1. Departments of Mathematics and Physics, Arab American University, 240 Jenin, Palestine;3. Department of Physics, Middle East Technical University, 06800 Ankara, Turkey
Abstract:OBJECTIVE: Inspiratory pressure (Pi) support delivered by a bilevel device has become the technique of choice for noninvasive home ventilation. Considerable progress has been made in the performance and functionality of these devices. The present bench study was designed to compare the various characteristics of 10 recently developed bilevel Pi devices under different conditions of respiratory mechanics. DESIGN: Bench model study. SETTING: Research laboratory, university hospital. MEASUREMENTS: Ventilators were connected to a lung model, the mechanics of which were set to normal, restrictive, and obstructive, that was driven by an ICU ventilator to mimic patient effort. Pressure support levels of 10 and 15 cm H(2)O, and maximum were tested, with "patient" inspiratory efforts of 5, 10, 15, 20, and 25 cm H(2)O. Tests were conducted in the absence and presence of leaks in the system. Trigger delay, trigger-associated inspiratory workload, pressurization capabilities, and cycling were analyzed. RESULTS: All devices had very short trigger delays and triggering workload. Pressurization capability varied widely among the machines, with some bilevel devices lagging behind when faced with a high inspiratory demand. Cycling was usually not synchronous with patient inspiratory time when the default settings were used, but was considerably improved by modifying cycling settings, when that option was available. CONCLUSIONS: A better knowledge of the technical performance of bilevel devices (ie, pressurization capabilities and cycling profile) may prove to be useful in choosing the machine that is best suited for a patient's respiratory mechanics and inspiratory demand. Clinical algorithms to help set cycling criteria for improving patient-ventilator synchrony and patient comfort should now be developed.
Keywords:bilevel ventilation devices  cycling  home ventilation  mechanical ventilation  pressure support  CC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw70"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cycling criterion  E"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw90"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  elastance  NIV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  noninvasive ventilation  PEEP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw130"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  positive end-expiratory pressure  Pi"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw150"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  inspiratory pressure  Psmax"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw170"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  maximum pressure support  PTPt"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw190"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  pressure-time product  pressure-time product values at 300 ms  pressure-time product values at 500 ms  Raw"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw250"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  airway resistance  Tiassist"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw270"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  duration of pressurization by the device  Tipat"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  cekeyw290"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  duration of inspiration set on the driving ventilator
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