多西他赛联合卡培他滨治疗转移性乳腺癌的临床观察

目的：观察多西他赛联合卡培他滨（希罗达）治疗转移乳性腺癌的疗效及不良反应。方法：56例乳腺癌患者采用多西他赛联合卡培他滨治疗，第1天静脉滴注多西他赛75mg／m^2；第1-14天口服卡培他滨900mg／m^2，每天2次，21d为1周期，4周期后评价疗效。结果：56例患者治疗后均取得较好疗效，不良反应主要为胃肠道反应、骨髓抑制和肝功能损害。均可经过对症支持治疗可逆性恢复，无治疗相关死亡患者。结论：多西他赛联合卡培他滨治疗转移性乳腺癌疗效较好，不良反应可耐受。

Clinical study of Docetaxel and Xeloda combination in the treatment of patients with metastatic breast cancer

Objective:To study the efficacy and toxicity of Docetaxel and Xeloda combination regimen in treatment of patients with metastatic breast cancer.Methods:Fifty-six patients received Docetaxel and Xeloda combination regimen,namely,Docetaxel 75 mg/m2 ivgtt,day1;Xeloda 900 mg/m2,twice daily.The regimen was repeated every 21 days and the clinical response was recorded after four cycles.Results:Fifty-six patients were evaluated that who obtain better curative effect.The main toxicities were gastrointestinal,myelos...