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深圳市女性泌尿生殖道支原体感染状况及药物敏感性分析
引用本文:蒋诗琴,沈时鹏,刘萍,资捷,王云霞,罗丽娅,王奕江. 深圳市女性泌尿生殖道支原体感染状况及药物敏感性分析[J]. 郧阳医学院学报, 2011, 30(2): 157-159
作者姓名:蒋诗琴  沈时鹏  刘萍  资捷  王云霞  罗丽娅  王奕江
作者单位:蒋诗琴,沈时鹏,王奕江,JIANG Shi-qin,SHEN Shi-peng,WANG Yi-jiang(深圳市福田区妇幼保健院药剂科,广东,深圳,518026);刘萍,王云霞,罗丽娅,LIU Ping,WANG Yun-xia,LUO Li-ya(深圳市福田区妇幼保健院妇产科,广东,深圳,518026);资捷,ZI Jie(深圳市福田区妇幼保健院检验科,广东,深圳,518026)
基金项目:2009年深圳市科技计划项目;项目编号200903193
摘    要:目的:了解深圳市女性泌尿生殖道支原体感染状况及支原体株对现有药物敏感性。方法:选取2009年1月-12月我市妇科门诊的泌尿生殖道感染患者及女性健康体检者,采集生殖道分泌物标本,进行解脲支原体(Uu)和人型支原体(Mh)的培养鉴定,对检出的支原体株进行药物敏感性检测。结果:支原体总感染率健康体检者为47.0%(169/320),泌尿生殖道感染患者为70.5%(125/176)。Uu、Mh及混合型感染率健康体检者分别为43.4%、0.6%和3.0%,泌尿生殖道感染患者分别为39.8%、0.6%和30.1%。Uu对强力霉素、美满霉素及交沙霉素敏感率较高,对氧氟沙星及左氧氟沙星耐药率较高。结论:支原体混合感染耐药性呈上升趋势。四环素类药物可以作为治疗解脲支原体感染的一线药物,尤其是强力霉素和美满霉素。

关 键 词:解脲支原体  泌尿生殖道感染  药敏分析

Analysis of Infection and Antibiotic Susceptibility of Mycoplasma in Genitourinary Tract in Female of Shenzhen Area
JIANG Shi-qin,SHEN Shi-peng,LIU Ping,ZI Jie,WANG Yun-xia,LUO Li-ya,WANG Yi-jiang. Analysis of Infection and Antibiotic Susceptibility of Mycoplasma in Genitourinary Tract in Female of Shenzhen Area[J]. Journal of Yunyang Medical College, 2011, 30(2): 157-159
Authors:JIANG Shi-qin  SHEN Shi-peng  LIU Ping  ZI Jie  WANG Yun-xia  LUO Li-ya  WANG Yi-jiang
Abstract:Objective To investigate the infections and antibiotic susceptibility of mycoplasma in genitourinary tract in female of Shenzhen area.Methods Ureaplasma urealyticum(Uu) and mycoplasma hominis(Mh) were isolated and cultured from the secretion samples of 176 patients with genitourinary tract infection as well as 362 healthy examination female.And the antibiotic susceptibility were determined in the cultured strains.Results The total positive rates of mycoplasma infection in healthy examination female and in patients with genitourinary tract infection were 47.0%(169/320) and 70.5%(125/176),respectively.The rates of single Uu,Mh and mixed infection in healthy examination female were 43.4%,0.6%,3.0%,while in patients were 39.8%,0.6%,30.1%,respectively.The antibiotic susceptibility results demonstrated that Uu were sensitive to vibramycin,minocycline and josamycin,but highly resistance to ofloxacin and levofloxacin.Conclusion The mixed infection of Uu and Mh,drug resistance were showed an increasing trend.The tetracyclines especially vibramycin and minocycline should be firstly considered for clinical treatment of Uu infection in Shenzhen area.
Keywords:Ureaplasma urealyticum  Genitourinary tract infection  Drug susceptibility analysis
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