颅内感染疾病患者医院感染调查分析

目的 调查颅内感染疾病患医院感染情况并探讨相关的危险因素。方法 回顾性调查3年来住院的156例化脓性、结核性、隐球菌性、病毒性脑膜炎或脑炎患及脑囊虫病患的医院感染情况。结果 51例患发生医院感染，医院感染率为32．69％，其中，隐球菌性脑膜炎的医院感染率最高(82．61％)，其次为结核性脑膜炎(35．56％)。感染部位以泌尿道感染(37．78％)、呼吸道感染(31．11％)多见。病原菌以革兰阴性杆菌为主。结论 医院感染发生与基础疾病严重程度，长期大剂量激素和抗菌药物的使用，住院时间长以及导尿、深静脉插管等因素有关。

Analysis of nosocomial infection in patients with intracranial infection

Objective To investigate nosocomial infection (NI) and its risk factors in patients with intracranial infection. Methods One hundred and fifty six NI in patients with purulent, tubercular, cryptococcus and virus meningitis or cephalitis and cerebral cysticercosis were investigated. Results Fifty one patients developed NI, 82.61% of which occurred in patients with cryptococcus meningitis, followed by tubercular meningitis ( 35.56% ); the most common infection sites were urinary tract ( 37.78% ) and respiratory tract ( 31.11% ), the majority of pathogens were Gram negative bacilli. Conclusion NI is associated with the severity of underlying diseases, massive use of hormones and antimicrobial agents, prolonged hospitalization and invasive procedures.