中西医结合治疗慢性阻塞性肺疾病急性加重期的疗效及对D-二聚体的影响

目的:探讨中西医结合治疗慢性阻塞性肺疾病急性加重期的疗效及对D-二聚体的影响。方法:选择2009年1月至2011年5月我院收治的62例慢性阻塞性肺疾病急性加重期患者作为观察对象,随机分为治疗组(32例)和对照组(30例),对照组常规给予低流量吸氧、抗感染、解痉平喘、化痰止咳、补液等治疗;治疗组在对照组的基础上,加清肺化痰祛瘀汤方治疗,比较两组的治疗效果及对D-二聚体的影响。结果:治疗组的总有效率明显优于对照组,差异具有统计学意义(P<0.05);对改善PaO2、PaCO2、D-二聚体及肺功能方面,治疗组明显优于对照组,差异具有统计学意义(P<0.05)。结论:清肺化痰祛瘀汤配合西医治疗慢性阻塞性肺疾病急性加重期患者疗效显著,且D-二聚体的下降幅度明显大于单纯西医治疗组,可以提高患者生活质量,值得临床推广。

Curative Effect of Traditional Chinese Medicine Combined with Western Medicine in Treatment of Chronic Obstructive Pulmonary Disease with Acute Exacerbation Period and Effect on D -Two Dimer

Objective ： To investigate the curative effect of traditional Chinese medicine combined with Western medicine in the treatment of chronic obstructive pulmonary disease with acute exacerbation period and the effect on D -two dimer. Methods ：62 ca- ses of chronic obstructive pulmonary disease with acute exacerbation period from January 2009 to May 2011 in our hospital were selected as the observation objects and were randomly divided into treatment group （ 32 cases） and control group （30 cases）. The control group were given conventional low flow oxygen therapy, anti - infection, spasmolysis, phlegm cough and fluid replacement and the treatment group on the basis of control group were given Qingfei Huatan Quyu Decoction. The effect and the influence on D - two dimmer were compared. Results ： The total effective rate in treatment group was significantly better than that of the control group and the difference was statistically significant （P 〈 0.05 ）. The improvement of PaO2 and PaCO2, D - two dimers and pal- monary function in the treatment group was significantly better than those of the control group and the difference was statistically significant （ P 〈 0.05 ）. Conclusion ： The treatment of Qingfei Huatan Quyu Decoction combined with western medicine in the treat- ment of chronic obstructive pulmonary disease with acute exacerbation period has the curative effects and the decrease of D - two dimer was significantly higher than that of the western medicine and it can improve the quality of life of patients and is worthy of clinical promotion.