| 摘 要： | To explore the effect of Buyang Huanwu Decoction(BHD)on platelet activating factor(PAF)contentin arterial blood pre-and post-arterial thrombosis in rats,male Wistar rats were randomly dividedinto 3 groups,the medicine group treated with BHD,the control group with dexamethasone liquid,and the blank group with distilled water.Oral administration was given for 14 consecutive days,oncedaily.Model of arterial thrombosis was established in the animals 2 hours after final medication,theblood content of PAF,dry weight(DW)and occlusion time(OT)of thrombus,and dry weight ofthrombus/body weight(TW/BW)ratio were observed.Results indicated that BHD could markedlylower the arterial blood content of PAF after thrombosis,increase the OT of thrombus,reduce the dryweight of thrombus and the TW/BW ratio(P<0.05).It is suggested that BHD can inhibit thepathologic PAF metabolism and formation and development of arterial thrombus.
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