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补肾方治疗慢性乙型肝炎临床研究
引用本文:唐苾芯,陈建杰,李运东,张小兵,顾伟. 补肾方治疗慢性乙型肝炎临床研究[J]. 上海中医药杂志, 2009, 43(4): 33-35
作者姓名:唐苾芯  陈建杰  李运东  张小兵  顾伟
作者单位:上海市浦东新区公利医院,上海,200135;上海中医药大学附属曙光医院,上海,200021
基金项目:浦东新区科技发展基金科技专项基金,浦东新区中医中青年骨干培养基金 
摘    要:目的 观察补肾方治疗肝肾亏虚兼湿热型慢性乙型肝炎的临床疗效.方法 选取肝肾亏虚兼湿热型慢性乙型肝炎患者共60例,随机分为补肾方治疗组和苦参素对照组各30例,疗程6个月,并随访6个月.观察两组患者血清HBV DNA阴转率、HBeAg阴转率、HBV DNA滴度变化及肝功能、中医证候积分变化.结果 治疗组随访时HBVDNA滴度下降较对照组明显(P<0.05);半年疗程结束时治疗组肝功能指标改善(P<0.01,P<0.05),其中TBIL、GLB的改善较对照组明显(P<0.01);治疗组中医证候疗效优于对照组,差异有统计学意义(P<0.05).结论 补肾方治疗肝肾亏虚兼湿热型慢性乙型肝炎有较为明确的抗病毒疗效,且能改善肝功能及临床症状.

关 键 词:慢性乙型肝炎  补肾方  苦参素  血清病毒学  中医证候  临床研究

Clinical Study of Kidney-Invigorating Prescription in Treating Chronic Hepatitis B
TANG Bi-xin CHEN Jian-jie LI Yun-dong ZHANG Xiao-bing GU Wei. Clinical Study of Kidney-Invigorating Prescription in Treating Chronic Hepatitis B[J]. Shanghai Journal of Traditional Chinese Medicine, 2009, 43(4): 33-35
Authors:TANG Bi-xin CHEN Jian-jie LI Yun-dong ZHANG Xiao-bing GU Wei
Affiliation:TANG Bi-xin1 CHEN Jian-jie2 LI Yun-dong2 ZHANG Xiao-bing1 GU Wei11.Shanghai Gongli Hospital of Pudong New Area2.Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Abstract:Objective To observe the efficacy of Kidney-Invigorating Prescription in treating chronic hepatitis B differentiated as liver-kidney insufficiency accompanied by dampness-heat retention. Methods A total of 60 were enrolled. They were randomized to receive either Kidney-Invigorating Prescription daily (the treatment group,n=30) or Marine Injection 400 mg daily (control group,n=30) for six months,and were followed up for six months. Negative transforming rate of HBV DNA and and HBeAg,titer of HBVDNA,indic...
Keywords:Chronic hepatitis B  Kidney-Invigorating Prescription  marine  serum virology  syndrome of Chinese medicine  clinical study  
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