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"Menstrual" migraine: towards a definition
Authors:EA MacGregor
Affiliation:The City of London Migraine Clinic and Department of Gynaecology St Bartholomew's Hospital, London, UK
Abstract:
"Menstrual" migraine, a term misused by both patients and doctors, lacks precise definition. This dissertation critically reviews papers on the subject and examines the problem from a clinical perspective. A definition is proposed that the term "menstrual" migraine should be restricted to attacks exclusively starting on or between day l ± 2 days of the menstrual cycle; the woman should be free from attacks at all other times of the cycle. This definition, unlike many used previously, links to a specific mechanism; the timing is consistent with oestrogen withdrawal. If this is correct, "oestrogen withdrawal" migraine may be a better term. Future studies, necessary to support or refute these proposals, are suggested.
Keywords:Migraine    oestrogen    oestrogen withdrawal    progesterone
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