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藓类植物回心草化学成分研究Ⅱ
引用本文:戴畅,刘屏,刘超,王波,陈若芸.藓类植物回心草化学成分研究Ⅱ[J].中国中药杂志,2006,31(13):1080-1082.
作者姓名:戴畅  刘屏  刘超  王波  陈若芸
作者单位:1. 中国人民解放军总医院,临床药理研究室,北京,100853
2. 中国医学科学院中国协和医科大学,药物研究所,北京,100050
基金项目:国家自然科学基金;北京市自然科学基金
摘    要:目的:研究民族草药藓类植物回心草Rhodobryum roseum的化学成分。方法:回心草95%乙醇提取物的醋酸乙酯部分,用硅胶、凝胶柱色谱进行成分分离纯化,通过物理化学和波谱方法鉴定结构。结果:从回心草的醋酸乙酯部分分离得到了8个化合物,结构鉴定为:芹菜素(apigenin,1)、槲皮素(quercetin,2)、齐墩果酸(oleanolic acid,3)、2α-羟基齐墩果酸(2α-hydroxyoleanolic acid,4)、2α-羟基乌苏酸(2α-hydroxyursolic acid,5)、原儿茶酸(protocatechuic acid,6)、对羟基苯甲酸(p-hydroxybenzoic acid,7)、对羟基桂皮酸(p-hydroxycinnamic acid,8)。结论:化合物1~8均为首次从该属植物中分离得到。

关 键 词:藓类植物  回心草  大叶藓  化学成分
文章编号:1001-5302(2006)13-1080-03
收稿时间:2005-11-25
修稿时间:2005-11-25

Studies on chemical constituents from moss Rhodobryum roseum Ⅱ
DAI Chang ;LIU Ping ;LIU Chao ;WANG Bo ;CHEN Ruo-yun.Studies on chemical constituents from moss Rhodobryum roseum Ⅱ[J].China Journal of Chinese Materia Medica,2006,31(13):1080-1082.
Authors:DAI Chang ;LIU Ping ;LIU Chao ;WANG Bo ;CHEN Ruo-yun
Institution:1. Department of Clinical Pharmacology , General Hospital of PLA, Beifing 100853, China; 2. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Abstract:OBJECTIVE: To study the chemical constituents from Rhodobryum roseum. METHOD: The compounds were isolated and purified by recrystallization and chromatography with silica gel and sephadex LH-20 column. Their structures were identified by physicochemical properties and spectral analysis. RESULT: Eight compounds were isolated and identified as apigenin (1), quercetin (2), oleanolic acid (3), 2alpha-hydroxyoleanolic acid (4), 2alpha-hydroxyursolic acid (5), protocatechuic acid (6), p-hydroxybenzoic acid (7), p-hydroxycinnamic acid (8). CONCLUSION: Compounds 1-8 were isolated from R. roseum for the first time.
Keywords:Moss  Rhodobryum roseum  chemical compounds
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