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Treatment of Thoracolumbar Vertebrate Fracture by Transpedicular Morselized Bone Grafting in Vertebrae for Spinal Fusion and Pedicle Screw Fixation
作者姓名:王金国  吴华  丁晓琳  刘玉田
作者单位:Department of Orthopedics Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Department of Orthopedics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Department of Spinal Surgery,Rizhao Hospital of Chinese Traditional Medicine,Department of Spinal Surgery,Rizhao Hospital of Chinese Traditional Medicine,Wuhan 430030,China Department of Spinal Surgery,Rizhao Hospital of Chinese Traditional Medicine Rizhao 276800,China,Wuhan 430030,China,Rizhao 276800,China,Rizhao 276800,China
摘    要:To enhance the fusion of graft bone in thoracolumbar vertebrae and minimize the postoperative loss of correction, short-segment pedicle screw fixation was reinforced with posterior moselizee bone grafting in vertebrae for spinal fusion in patients with thoracrolumbar vertebrate fractures. Seventy patients with thoracrolumbar vertebrate fractures were treated by short-segment pedicle screw fixation and were randomly divided into two groups. Fractures in group A (n=20) were rein-forced with posterior morselized bone grafting in vertebrae for spinal fusion, while patients group B (n=50) did not receive the morselized bone grafting for bone fusion. The two groups were compared in terms of kyphotic deformity, anterior vertebral height, instrument failure and neurological functions after the treatment. Frankel grading system was used for the evaluation of neurological evaluation and Denis scoring scale was employed for pain assessment. The results showed that the kyphosis correction was achieved in both group A and group B (group A: 6.4 degree; group B: 5.4 degree)/At the end of follow-up, kyphosis correction was maintained in group A but lost in group B (P=0.0001). Postoperatively, greater anterior height was achieved in group A than in group B (P〈0.01). During follow-up study, anterior vertebral height was maintained only in Group A (P〈0.001). Both group A and group B showed good Denis pain scores (P1 and P2) but group A outdid group B in terms of control of severe and constant pain (P4 and P5). By Frankel criteria, the changes in neurological functions in group A was better than those of group B (P〈0.001). It is concluded that reinforcement of short-segment pedicle fixation with morselized bone grafting for the treatment of patients with thoracolumbar vertebrae fracture could achieve and maintain kyphosis correction, and it may also increase and maintain anterior vertebral height. Morselized bone grafting in vertebrae offers immediate spinal stability in patients with th

关 键 词:腰椎断裂  畸形  骨移植  椎骨
收稿时间:15 July 2007

Treatment of thoracolumbar vertebrate fracture by transpedicular morselized bone grafting in vertebrae for spinal fusion and pedicle screw fixation
Jinguo?Wang,Hua?Wu,Xiaolin?Ding,Yutian?Liu.Treatment of Thoracolumbar Vertebrate Fracture by Transpedicular Morselized Bone Grafting in Vertebrae for Spinal Fusion and Pedicle Screw Fixation[J].Journal of Zuazhong University of Science and Technology: Medical Edition,2008,28(3):322-326.
Authors:Jinguo Wang  Hua Wu  Xiaolin Ding  Yutian Liu
Institution:1. Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;Department of Spinal Surgery, Rizhao Hospital of Chinese Traditional Medicine, Rizhao 276800, China
2. Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
3. Department of Spinal Surgery, Rizhao Hospital of Chinese Traditional Medicine, Rizhao 276800, China
Abstract:To enhance the fusion of graft bone in thoracolumbar vertebrae and minimize the postoperative loss of correction,short-segment pedicle screw fixation was reinforced with posterior mosel-izee bone grafting in vertebrae for spinal fusion in patients with thoracrolumbar vertebrate fractures.Seventy patients with thoracrolumbar vertebrate fractures were treated by short-segment pedicle screw fixation and were randomly divided into two groups.Fractures in group A(n=20) were reinforced with posterior morselized bone grafting in vertebrae for spinal fusion,while patients group B(n=50) did not receive the morselized bone grafting for bone fusion.The two groups were compared in terms of kyphotic deformity,anterior vertebral height,instrument failure and neurological functions after the treatment.Frankel grading system was used for the evaluation of neurological evaluation and Denis scoring scale was employed for pain assessment.The results showed that the kyphosis correction was achieved in both group A and group B(group A:6.4 degree;group B:5.4 degree)/At the end of follow-up,kyphosis correction was maintained in group A but lost in group B(P=0.0001).Postoperatively,greater anterior height was achieved in group A than in group B(P<0.01).During follow-up study,anterior vertebral height was maintained only in Group A(P<0.001).Both group A and group B showed good Denis pain scores(P1 and P2) but group A outdid group B in terms of control of severe and constant pain(P4 and P5).By Frankel criteria,the changes in neurological functions in group A was better than those of group B(P<0.001).It is concluded that reinforcement of short-segment pedicle fixation with morselized bone grafting for the treatment of patients with thoracolumbar vertebrae fracture could achieve and maintain kyphosis correction,and it may also increase and maintain anterior vertebral height.Morselized bone grafting in vertebrae offers immediate spinal stability in patients with thoracolumbar vertebrate fractures,decreases the instrument failure and provides better postoperative pain control than without the morselized bone grafting.
Keywords:thoracolumbar vertebrae fracture  kyphotic deformity  pedicle screw  morselized bone  grafting in vertebrae
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