| 地洛他定治疗过敏性鼻炎的临床疗效和安全性评价 |
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| 引用本文： | 王鹏,王建中,黄新生,谢晓凤,周旭,罗雪梅,黄凤娥.地洛他定治疗过敏性鼻炎的临床疗效和安全性评价[J].中国临床医学,2009,16(2):281-282. |
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| 作者姓名： | 王鹏 王建中 黄新生 谢晓凤 周旭 罗雪梅 黄凤娥 |
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| 作者单位： | 复旦大学附属中山医院耳鼻喉科,上海,200032 |
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| 摘 要： | 目的：比较地洛他定与氯雷他定治疗过敏性鼻炎的有效性和安全性。方法：入选过敏性鼻炎患者57例,其中研究组30例口服地洛他定（5mg/片）,每日1次,每次1片;对照组27例口服氯雷他定（10mg/片）,每日1次每次1片。两组疗程均为14d,观察两组疗效和不良反应。结果：研究组治疗有效率为96.7%,对照组治疗有效率为88.9%,两组间差异无统计学意义（P〉0.05）。所有患者在研究过程中均未出现严重不良事件,不良反应的发生率研究药和对照药分别为16.7%和11.1%,两者之间无显著性差异。结论：地洛他定片治疗过敏性鼻炎安全、有效。
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| 关 键 词： | 地洛他定 氯雷他定 鼻炎 临床实验 |
Evaluation of the Efficacy and Safety of Desloratadine in Treating Allergic Rhinitis |
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| WANG Peng,WANG Jianzhong,HUANG Xinsheng,XIE Xiaofeng,ZHOU Xu,LUO Xuemei,HUANG Fenge.Evaluation of the Efficacy and Safety of Desloratadine in Treating Allergic Rhinitis[J].Chinese Journal Of Clinical Medicine,2009,16(2):281-282. |
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| Authors: | WANG Peng WANG Jianzhong HUANG Xinsheng XIE Xiaofeng ZHOU Xu LUO Xuemei HUANG Fenge |
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| Institution: | WANG Peng WANG Jianzhong H UANG Xinsheng XIE Xiaofeng ZHOU Xu LUO Xuemei HUANG Fenge Department of Otolaryngology,Zhongshan Hospital,Fudan University,Shanghai 200032 |
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| Abstract: | Objective:To evaluate the efficacy and safety of desloratadine in treating allergic rhinitis. Methods:A randomized and double-blind clinical trail was conducted. Totally 57 patients with allergic rhinitis were randomly assigned into two groups. The study group of 30 patients took desloratadine tablet 5 mg, po, qd. The control group of 27 patients took loratadinum tablet 10 mg, po, qd. The period of treatment of both groups was 14d. Results:The effective rate of desloratadine was 96.7%, while it was 88.9% in... |
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| Keywords: | Desloratadine Loratadine Rhinitis Clinical trails |
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