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Age-related decline in cold tolerance can be retarded by brain stimulation |
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| Authors: | M.I. Talan B.T. Engel J.R. Whitaker |
| Abstract: | The sharp decline in capacity of old C57BL/6J male mice to maintain body temperature during 3-hr cold exposure can be delayed and even partly restored after 15, 30-min, daily sessions of hypothalamic self-stimulation. In control experiments it was demonstrated that electrical stimulation of “rewarding” areas of hypothalamus itself is sufficient for improvement of the age-related deterioration of thermoregulatory ability. |
| Keywords: | Cold exposure Thermoregulation Age Intracranial self-stimulation “Rewarding”areas of hypothalamus Mice |
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