| 脊髓损伤早期及制动后大鼠股骨远端组织形态学观察 |
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| 引用本文： | 余文超,刘岩,袁文,郭永飞,曹振羽,邹翰林.脊髓损伤早期及制动后大鼠股骨远端组织形态学观察[J].创伤外科杂志,2011,13(5):446-450. |
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| 作者姓名： | 余文超 刘岩 袁文 郭永飞 曹振羽 邹翰林 |
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| 作者单位： | 余文超 (第二军医大学附属长征医院骨科,上海,200003) ； 刘岩 (第二军医大学附属长征医院骨科,上海,200003) ； 袁文 (第二军医大学附属长征医院骨科,上海,200003) ； 郭永飞 (第二军医大学附属长征医院骨科,上海,200003) ； 曹振羽 (第二军医大学附属长征医院骨科,上海,200003) ； 邹翰林 (第二军医大学附属长征医院骨科,上海,200003) ； |
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| 基金项目： | 上海市科学技术委员会科研计划项目资助 |
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| 摘 要： | 目的 建立大鼠脊髓损伤及废用性模型(制动),观察建模早期两种模型大鼠股骨远端破骨细胞数量及动态组织形态学的改变.方法 24只SD大鼠随机分为3组(每组8只).对照组:切除T10椎板,不损伤硬膜及脊髓;脊髓损伤(SCI)组:切除T10椎板后行Allen's法(60gocm动能)造成脊髓损伤;制动组:采用大鼠双侧腿-尾缝合...
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| 关 键 词： | 脊髓损伤 骨质疏松 股骨 破骨细胞 |
Histomorphometry observation on the distal femur after spinal cord injury and immobilization in rats |
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| YU Wen-chao,LIU Yan,YUAN Wen,et al..Histomorphometry observation on the distal femur after spinal cord injury and immobilization in rats[J].Journal of Traumatic Surgery,2011,13(5):446-450. |
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| Authors: | YU Wen-chao LIU Yan YUAN Wen |
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| Institution: | YU Wen-chao,LIU Yan,YUAN Wen,et al.(Department of Orthopaedics,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China) |
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| Abstract: | Objective Rats models with both spinal cord injury(SCI)and disuse atrophy were established,so as to make an observation and comparison on the number of osteoclast and dynamic histomorphometry studies at the distal femoral osteoclast changes.Methods A total of 24 male rats were randomly divided into three groups: control group(sham operation group),immobilization group and the SCI group.After anesthesia,T10 vertebral plate resection was performed to rats in both the SCI group and the control group,with weigh... |
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| Keywords: | spinal cord injury osteoporosis femur osteoclast |
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