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糖尿病肾病中医证型与血浆TXB_2 6-keto-PGF_(Iα)的关系探讨
引用本文:唐红,徐蓉娟,胡健炜,朱良争,钟家宝.糖尿病肾病中医证型与血浆TXB_2 6-keto-PGF_(Iα)的关系探讨[J].辽宁中医杂志,1997(1).
作者姓名:唐红  徐蓉娟  胡健炜  朱良争  钟家宝
作者单位:上海中医药大学附属龙华医院
摘    要:选择非胰岛素依赖型糖尿病(NIDDM)肾病气虚血瘀型31例、气阴两虚型30例,分别测定血浆血栓素B2(TXB2)和6-酮-前列腺素FIα(6-keto-PGFIα)。结果显示气虚血瘀型患者TXB2明显升高,6-keto-PGFIα明显降低,与气阴两虚组比有显著性差异(P<0.01~0.05)。提示血浆TXB2及PGFIα的改变与NIDDM肾病气虚血瘀证关系密切,并可作为NIDDM肾病中医辨证分型的参考指标。

关 键 词:NIDDM肾病  气虚血瘀  TXB_2  6-keto-PGF_(Iα)

On the relationship between plasma TXB 2 6-Keto-PGF Ⅰα and typology of TCM \ of diabetic renopathy
Tang Hong,Xu Rongjuan,Hu Jianwei et al.On the relationship between plasma TXB 2 6-Keto-PGF Ⅰα and typology of TCM \ of diabetic renopathy[J].Liaoning Journal of Traditional Chinese Medicine,1997(1).
Authors:Tang Hong  Xu Rongjuan  Hu Jianwei
Abstract:NIDDM nephropathy patients were chosen in the study,of them 31 cases were Qi-deficency-Blood stasis type,30 cases were Both Qi and Yin deficency type,according to TCM diagnosis.The concentration of serum TXA 2 and 6-keto-PGF Iα in each patient were determined.It shows the concentration of serum TXA 2 in Qi deficency-Blood stasis group is significantly higher than that of controld and the concentration of serum 6-keto-PGF Iα is significantly lower than that of control.There are no difference of serum TXA 2 and 6-keto-PGF Iα in Both Qi and Yin,deficency group,comparing with the control.The result shows that the changing of the concertration of serum TXA 2 and PGF Iα is closely correlated with the type of Qi deficency-Blood stasis in NIDDM nephroathy patient.It can be used as the reference of TCM diagnosis.
Keywords:NIDDM nethropathy  Qi deficiency Blood stasis  TXB  2  6-keto-PGF    
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