Application of microsatellite typing for the investigation of a cluster of cases of Candida albicans candidaemia |
| |
| Authors: | S. Beretta,J. P. Fulgencio,A. Enache-Angoulvant,C. Bernard,S. El Metaoua,T. Ancelle,M. Denis, C. Hennequin |
| |
| Affiliation: | 1. Laboratoire de Parasitologie-Mycologie, Paris, France;2. Service de Réanimation Chirurgicale, Paris, France;3. Laboratoire Commun de Biologie Moléculaire, Hôpital St Antoine, Paris, France;4. Laboratoire de Parasitologie-Mycologie, Hôpital Cochin, Paris, France;5. Unité d''Hygiène, Hôpital Tenon, Paris, France |
| |
| Abstract: | ![]()
A cluster of cases of Candida albicans candidaemia in a surgical intensive care unit was investigated. The probability of such a cluster during a single month was highly significant compared with the frequency of candidaemia in the previous year. A molecular typing method, based on length analysis of three (EF3, CDC3, HIS3) microsatellite-containing regions, was used to investigate isolates from patients in and outside the ward. This demonstrated the involvement of different strains, indicating the absence of cross-transmission among patients. Results of microsatellite typing can be obtained almost in real-time, which is particularly useful in an outbreak context. |
| |
| Keywords: | Candida albicans candidaemia microsatellite repeats molecular typing outbreak typing |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
