医院内革兰阳性球菌感染的调查及耐药分析

目的]了解医院内感染的革兰阳性球菌的分布及耐药情况，指导临床医生合理应用抗生素，防止耐药菌株的爆发流行。方法]药敏试验采用K-B纸片扩散法，结果用WHONET5软件进行统计学分析。结果]革兰阳性球菌在院内感染中所占比例为25％，主要是肠球菌和葡萄球菌，肠球菌对所监测的抗生素均有不同程度的耐药，金黄色葡萄球菌除未发现万占霉素耐药外对其他监测的抗生素均有不同程度的耐药。结论]革兰阳性球菌在医院感染中仍占有重要地位，MRS和VRE的感染较常见，对革兰阳性球菌进行规范的耐药监测工作是十分必要和重要的。

Clinical analysis of resistance and survey of gram - positive cocci infection in hospital

Objective ] To understand distribution and resistant of gram - positive cocci in hospital infection and to direct clinical doctor in use of antibioties reasonably to prevent resistant strain outbreak and prevalenee. Methods ] Antibiotie suseeptivity test was done by Kirby -Bauer method. The result was analyzed by WHONET5 software, Results] Gram- positive cocci were 25% in hospital infection, of which enterocoeei and staphyloeoeei were major. Enteroeoeeus expressed resistanee to antibioties to some degree, Stapylococeus aureus expressed resistance to antibiotics to some degree except for vancomycin. Conclusion ] Gram - positive cocci are still important in hospital infection. MRS and VRE frequently appear. It is quite necessary and important that we normatively monitor resistance of gram - positive cocci.