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| 耳草属植物的化学研究I.黄毛耳草中环烯醚萜甙的分离和鉴定 | |
| 引用本文： | 彭江南,冯孝章,李光玉,梁晓天. 耳草属植物的化学研究I.黄毛耳草中环烯醚萜甙的分离和鉴定[J]. 药学学报, 1997, 32(12): 908-913 |
| 作者姓名： | 彭江南 冯孝章 李光玉 梁晓天 |
| 作者单位： | [1]军事医学科学院放射医学研究所，北京100850 [2]中国医学科学院，中国协和医科大学药物研究所，北京100050 |
| 摘 要： | 从中药黄毛耳草(Hedyotis chrysotricha)中分离鉴定出10个环烯醚萜类化合物,其中8个已知物为:车叶草甙(asperuloside,1),鸡屎藤甙甲酯(scandoside methyl ester,2),车叶草酸(asperulosidic acid,3),去乙酰车叶草酸(deacetyl asperulosidic acid,4),马钱子素(loganin,5),去乙酰车叶草甙(deacetylasperuloside,6),乙酰鸡屎藤甙甲酯(acetyl scandosidemethylester,7),6β-羟基京尼平(6β-hydroxy-genipin,8);2个新化合物命名为耳草甙(hedyoside,9),6′-乙酰车叶草甙(6′-acetylasperuloside,10)。除车叶草甙外均为首次从该植物得到,6β-羟基京尼平为首次从天然界发现。 |
| 关 键 词： | 黄毛耳草 环烯醚萜 耳草甙 6′-乙酰车叶草甙 |
| 收稿时间： | 1996-11-10 |
CHEMICAL INVESTIGATION OF GENUS HEDYOTIS II. ISOLATION AND IDENTIFICATION OF IRIDOIDS FROM HEDYOTIS CHRYSOTRICHA |
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| J N Peng,X Z Feng,G Y Li,X T Liang. CHEMICAL INVESTIGATION OF GENUS HEDYOTIS II. ISOLATION AND IDENTIFICATION OF IRIDOIDS FROM HEDYOTIS CHRYSOTRICHA[J]. Acta pharmaceutica Sinica, 1997, 32(12): 908-913 | |
| Authors: | J N Peng X Z Feng G Y Li X T Liang |
| Affiliation: | Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050. |
| Abstract: | Many species of genus Hedyotis (Rubiaceae) were used as folk medicine for treatment of cold, inflammation, cancer and etc. in China. The alcoholic extract of the whole plant of H. chrysotricha showed good hepatoprotective effects. From the alcoholic extract ten iridoids were isolated and their structures were elucidated as: asperuloside (1), scandoside methyl ester (2), asperulosidic acid (3), deacetyl asperulosidic acid (4), loganin (5), deacetyl asperuloside (6), acetyl scandoside methyl ester (7), 6 beta-hydroxy-genipin (8) and two new compounds named hedyoside (9) and 6'-acetylasperuloside (10), by means of chemical and spectral methods. |
| Keywords: | Iridoids Hedyoside 6′-Acetyl asperuloside Hedyotis chrysotricha |
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