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心肌挫伤后心肌酶谱和心脏肌钙蛋白-T的含量变化
引用本文:闵家新,朱佩芳,王正国,刘宝松,翁格文. 心肌挫伤后心肌酶谱和心脏肌钙蛋白-T的含量变化[J]. 第三军医大学学报, 2000, 22(2): 139-141
作者姓名:闵家新  朱佩芳  王正国  刘宝松  翁格文
作者单位:第三军医大学附属大坪医院野战外科研究所第四研究室,重庆,400042;第三军医大学附属大坪医院野战外科研究所第四研究室,重庆,400042;第三军医大学附属大坪医院野战外科研究所第四研究室,重庆,400042;第三军医大学附属大坪医院野战外科研究所第四研究室,重庆,400042;第三军医大学附属大坪医院野战外科研究所第四研究室,重庆,400042
基金项目:国家自然科学基金!(39630330)
摘    要:目的:观察心脏肌钙蛋白-T(cTn-T)和心肌酶谱(ME)在心肌挫伤(CC)后含量变化及其对CC的诊断价值。方法:采用兔钝性胸部创伤(BCT)模型,致成中度至重度CC,分别在伤前、伤后4、8和24h抽箅测定血清cTn-T和ME含量。结果:伤后4h,血精cTn-T和ME含量明显升高(P〈0.01),持续至伤后24h。其中cTn-T在伤后24h升高最为明显,ME有下降,但仍然明显高于伤前(P〈0.01

关 键 词:心肌挫伤  心脏肌钙蛋白-T  心肌酶谱  钝性胸  部创伤

Experimental study of comparison of diagnosis of cardiac contusion in rabbits
MIN Jia-xin,ZHU Pei-fang,WANG Zheng-guo,LIU Bao-song,WENG Ge-wen. Experimental study of comparison of diagnosis of cardiac contusion in rabbits[J]. Acta Academiae Medicinae Militaris Tertiae, 2000, 22(2): 139-141
Authors:MIN Jia-xin  ZHU Pei-fang  WANG Zheng-guo  LIU Bao-song  WENG Ge-wen
Affiliation:MIN Jia-xin, ZHU Pei-fang, WANGZheng-guo, LIU Bao-song,WENG Ge-wen(Research Institute of Field Surgery, Daping Hospital, Third Military Medical University,Chongqing 400042)
Abstract:Objective: To observe the changes of the cardiac troponin T (cTn T) and myocardial enzyme (ME) in plasma and to assess their value in diagnosis of cardiac contusion (CC) after blunt chest trauma (BCT). Methods: Before and at the 4th, 8th and 24th h after the model of BCT was established in rabbits, the cTn T and ME contents were determined. Results: The contents of cTn T and ME were remarkably increased from the 4th to 24th h after BCT (P<0.01). The content of cTn T reached its peak while that of ME was slightly decreased at the 24th h after BCT. The latter was still significantly higher than that before the trauma (P<0.01). Conclusion: It is helpful for diagnosis of CC after BCT to measure the changes of cTn T and ME contents in plasma. CTn T is more sensitive than ME in diagnosis of CC after BCT.
Keywords:cardiac contusion  troponin T  myocardial enzyme  blunt chest trauma
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