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Interrelationship between TP53 gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma |
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| Authors: | André S Khayat Adriana C Guimarães Danielle Q Calcagno Aline D Seabra Eleonidas M Lima Mariana F Leal Mário HG Faria Silvia HB Rabenhorst Paulo P Assumpção Samia Demachki Marília AC Smith Rommel R Burbano |
| Affiliation: | 1. Human's Cytogenetics Laboratory, Institute of Biological Sciences, Federal University of Pará, Av Augusto Correa 01, 66075-900, Belém, PA, Brazil 2. Biology Department, Campus Ministro Reis Velloso/Parnaíba, Federal University of Piauí, Piauí, PI, Brazil 3. Genetics Division, Department of Morphology, Federal University of S?o Paulo, S?o Paulo, SP, Brazil 4. Molecular's Genetics Laboratory, Department of Pathology, Medical School, Federal University of Ceará, Fortaleza, CE, Brazil 5. Jo?o de Barros Barreto University Hospital, Federal University of Pará, Belém, PA, Brazil |
| Abstract: | BackgroundThis study evaluates the existence of numerical alterations of chromosome 17 and TP53 gene deletion in gastric adenocarcinoma. The p53 protein expression was also evaluated, as well as, possible associations with clinicopathological characteristics. |
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